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Gastric Squamous Cell Carcinoma - Horse (view source)
Revision as of 19:18, 10 August 2010
, 19:18, 10 August 2010→Diagnosis
==Diagnosis==
==Diagnosis==
Diagnosis is usually made by exclusion of other causes of weight loss and gastroscopy. Haematology may reveal a normocytic anaemia, neutrophilia and hypoalbuminaemia.<ref name="Olsen2">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173.</ref> Hypercalcaemia of malignancy may be noted.<ref name="Talor">Taylor S.D, Haldorson, G.J, Vaughan, B, Pusterla, N (2009) Gastric neoplasia in horses. ''J Vet Intern Med'', 23(5):1097-102.</ref> [[Colic Diagnosis - Abdominocentesis|Abdominocentesis]] may demonstrate abnormal peritoneal effusions with neoplastic cells. Nodules lining the peritoneum may be seen at ''post-mortem'' examination.<ref name="Olsen2">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173.</ref>
Diagnosis is usually made by exclusion of other causes of weight loss and '''gastroscopy'''. '''Haematology''' may reveal a normocytic anaemia, neutrophilia and hypoalbuminaemia.<ref name="Olsen2">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173.</ref> '''Hypercalcaemia of malignancy''' may also be noted.<ref name="Talor">Taylor S.D, Haldorson, G.J, Vaughan, B, Pusterla, N (2009) Gastric neoplasia in horses. ''J Vet Intern Med'', 23(5):1097-102.</ref> [[Colic Diagnosis - Abdominocentesis|Abdominocentesis]] may demonstrate abnormal peritoneal effusions with neoplastic cells. [[Colic Diagnosis - Abdominal Ultrasound|Abdominal ultrasound]] may also help to locate metastases. The most common finding at ''post-mortem'' in the stomach is a single ulcerated, necrotic mass in the squamous region.<ref name="Talor">Taylor S.D, Haldorson, G.J, Vaughan, B, Pusterla, N (2009) Gastric neoplasia in horses. ''J Vet Intern Med'', 23(5):1097-102.</ref> There may also be nodules lining the peritoneum.<ref name="Olsen2">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173.</ref>
==Treatment and Prognosis==
==Treatment and Prognosis==