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Supportive care should be given to cats and dogs with clinical toxoplasmosis as required. The specific treatment for ''Toxoplasma gondii'' infection is clindamycin, at a dose of 12-25mg/kg per os every 12 hours. Treatment should generally be given for four weeks, but should continue for at least two weeks after clinical signs have disppeared. Side effects can include acute vomiting and diarrhoea, but stopping treatment for a day or so before reintroducing the drug usually resolves this. Alternatively, a trimethoprim-potentiated sulphonamide may be used at 15mg/kg orally, twice daily for 4 weeks. This is useful in animals where clindamycin is not tolerated or is ineffective in treating CNS toxoplasmosis. Trimethoprim-sulphonamides can cause depression, anaemia, leukopenia and thrombocytopenia, so a complete blood cell cound should be performed every two weeks to monitor this. Macrolides such as spiramycin, azithromycin and clarithromycin may also be effective against toxoplamosis, but have not yet been evaluated in cats and dogs.
 
Supportive care should be given to cats and dogs with clinical toxoplasmosis as required. The specific treatment for ''Toxoplasma gondii'' infection is clindamycin, at a dose of 12-25mg/kg per os every 12 hours. Treatment should generally be given for four weeks, but should continue for at least two weeks after clinical signs have disppeared. Side effects can include acute vomiting and diarrhoea, but stopping treatment for a day or so before reintroducing the drug usually resolves this. Alternatively, a trimethoprim-potentiated sulphonamide may be used at 15mg/kg orally, twice daily for 4 weeks. This is useful in animals where clindamycin is not tolerated or is ineffective in treating CNS toxoplasmosis. Trimethoprim-sulphonamides can cause depression, anaemia, leukopenia and thrombocytopenia, so a complete blood cell cound should be performed every two weeks to monitor this. Macrolides such as spiramycin, azithromycin and clarithromycin may also be effective against toxoplamosis, but have not yet been evaluated in cats and dogs.
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In toxoplasma-induced uveitis have intense
Cats with Toxoplasma-induced uveitis have intense
   
intraocular inflammatory reactions that commonly lead
 
intraocular inflammatory reactions that commonly lead
 
to lens luxation and glaucoma. Thus, cats with uveitis
 
to lens luxation and glaucoma. Thus, cats with uveitis
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