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The toxoplasmosis patient does not usually require hospitalisation, unless they are suffering severe disease or cannot maintain adqequate nutrition or hydration unaided. Patients showing neurological signs should also be confined and monitored.
 
The toxoplasmosis patient does not usually require hospitalisation, unless they are suffering severe disease or cannot maintain adqequate nutrition or hydration unaided. Patients showing neurological signs should also be confined and monitored.
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Supportive care should be given to cats and dogs with clinical toxoplasmosis as required. The specific treatment for ''Toxoplasma gondii'' infection is clindamycin, at a dose of 12-25mg/kg per os every 12 hours. Treatment should generally be given for four weeks, but should continue for at least two weeks after clinical signs have disppeared. Side effects can include acute vomiting and diarrhoea, but stopping treatment for a day or so before reintroducing the drug usually resolves this. Alternatively, a trimethoprim-potentiated sulphonamide may be used at 15mg/kg orally, twice daily for 4 weeks. This is useful in animals where clindamycin is not tolerated or is ineffective in treating CNS toxoplasmosis.
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Supportive care should be given to cats and dogs with clinical toxoplasmosis as required. The specific treatment for ''Toxoplasma gondii'' infection is clindamycin, at a dose of 12-25mg/kg per os every 12 hours. Treatment should generally be given for four weeks, but should continue for at least two weeks after clinical signs have disppeared. Side effects can include acute vomiting and diarrhoea, but stopping treatment for a day or so before reintroducing the drug usually resolves this. Alternatively, a trimethoprim-potentiated sulphonamide may be used at 15mg/kg orally, twice daily for 4 weeks. This is useful in animals where clindamycin is not tolerated or is ineffective in treating CNS toxoplasmosis. Trimethoprim-sulphonamides can cause depression, anaemia, leukopenia and thrombocytopenia, so a complete blood cell cound should be performed every two weeks to monitor this. Macrolides such as spiramycin, azithromycin and clarithromycin may also be effective against toxoplamosis, but have not yet been evaluated in cats and dogs.
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If trimethoprim-sulphonamide combinations
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are used, a complete blood cell count should be
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performed every two weeks to monitor for the development
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of macrocytic anaemia.
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Pyrimethamine combined with a sulphonamide drug
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is effective for the treatment of human toxoplasmosis,
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but commonly results in toxicity in cats. The macrolide
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antibiotics, spiramycin, azithromycin and clarithromycin,
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may be effective alternate anti-Toxoplasma drugs
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but have not been evaluated for the treatment of clinical
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feline toxoplasmosis. Minocycline is effective for the
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treatment of ocular toxoplasmosis in rabbits. It is possible
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that the related synthetic tetracycline, doxycycline,
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administered at 5 mg/kg orally every 12 hours for four
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weeks, may also be effective for the treatment of clinical
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feline toxoplasmosis.
   
Cats with Toxoplasma-induced uveitis have intense
 
Cats with Toxoplasma-induced uveitis have intense
 
intraocular inflammatory reactions that commonly lead
 
intraocular inflammatory reactions that commonly lead
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**If kept indoors, only canned food should be fed and vermin controlled
 
**If kept indoors, only canned food should be fed and vermin controlled
 
**ELISA to check if seropositive
 
**ELISA to check if seropositive
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For animals other than humans, treatment is seldom warranted. Sulfadiazine (15-25 mg/kg) and pyrimethamine (0.44 mg/kg) act synergistically and are widely used for treatment of toxoplasmosis. While these drugs are beneficial if given in the acute stage of the disease when there is active multiplication of the parasite, they will not usually eradicate infection. These drugs are believed to have little effect on the bradyzoite stage. Certain other drugs, including diaminodiphenylsulfone, atovaquone, and spiramycin are also used to treat toxoplasmosis in difficult cases. Clindamycin is the treatment of choice for dogs and cats, at 10-40 mg/kg and 25-50 mg/kg respectively, for 14-21 days.
      
==Zoonosis==
 
==Zoonosis==
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