− | Within two to three days of clindamycin or trimethoprim-sulphonamide administration, pyrexia and many other acute signs should begin to resolve. Animals with these clinical signs have a good prognosis. If a response is not seen within this time period, an alternative anti-''Toxoplasma'' drug should be considered. However, anti-''Toxoplasma'' drugs are unlikely to completely eradicate the organism from the host, and so recurrences are common. | + | Within 2-3 days of clindamycin or trimethoprim-sulphonamide administration, most clinical signs should begin to resolve and the prognosis is good. However, anti-''Toxoplasma'' drugs are unlikely to completely eradicate the organism from the host, and so recurrences are common. Ocular and CNS toxoplasmosis respond more slowly to therapy and carry a worse prognosis. Some neuromuscular signs may be persistent due to permanent nervous damage. Animals with hepatic or pulmonary disease have a poor prognosis. |