Changes

*In some primates it acts as a [[:Category:Primary Lymphoid Tissue|primary lymphoid organ]]

*In some primates it acts as a [[:Category:Primary Lymphoid Tissue|primary lymphoid organ]]

*Bone marrow is also a [[:Category:Secondary Lymphoid Tissue|secondary lympoid tissue]]

*Bone marrow is also a [[:Category:Secondary Lymphoid Tissue|secondary lympoid tissue]]

<p>It has little involvement in the primary immune response, but the migration of [[B cell differentiation - WikiBlood#Memory cells|memory cells]] into the marrow from the [[Spleen - Anatomy & Physiology|spleen]] and [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] means that during a subsequent exposure to an antigen it produces significant amounts of antibodies.</p>

<p>It has little involvement in the primary immune response, but the migration of [[B cell differentiation#Memory cells|memory cells]] into the marrow from the [[Spleen - Anatomy & Physiology|spleen]] and [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] means that during a subsequent exposure to an antigen it produces significant amounts of antibodies.</p>

===Others===

===Others===

*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation - WikiBlood#Plasma cells|plasma cells]]) reside in the bone marrow

*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside in the bone marrow

*[[Macrophages|Macrophages]] and [[T cell differentiation - WikiBlood#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood

*[[Macrophages|Macrophages]] and [[T cell differentiation - WikiBlood#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood

**A process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]]

**A process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]]

[[Category:Primary Lymphoid Tissue]]

[[Category:Primary Lymphoid Tissue]]