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Lymphoma (view source)

Revision as of 19:51, 18 August 2010

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'''Renal''' lymphoma also occurs in cats and affeted animals will present with signs similar to renal failure.
 
'''Renal''' lymphoma also occurs in cats and affeted animals will present with signs similar to renal failure.
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==Gastric==
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* Diffuse infiltration of [[Lymphocytes - Introduction|lymphocytes]].
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* Seen primarlity in dogs and cattle, but also in the pig and cat.
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==Intestinal==
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* Lymphoma occurs in both the small and [[Large Intestine - Anatomy & Physiology|large intestine]]s.
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* Is a relatively common neoplasm of the cat and dog.
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* Causes a diffuse spread of neoplastic lymphocytes through the mucosa and the rest of the wall.
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** Leads to malabsorption and therefore [[Diarrhoea|diarrhoea]] and the development of a protein losing enteropathy.
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=Alimentary Lymphoma=
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Intestinal tumours are uncommon accounting for less than 10% of all tumours in dogs and cats and 22% of gastrointestinal tumours in dogs and 35% in cats. Intestinal tumours in dogs and cats are usually malignant, alimentary lymphoma (AL) being the most common type of intestinal malignancy in cats and the second most frequent malignancy to affect the intestine in dogs. Primary AL may be differentiated from widespread multicentric lymphoma by the fact that the lymph nodes are not affected with AL. AL must also be distinguished from localised lymphoma that affects the mesenteric lymph node only with no intestinal involvement, which should be classified in the miscellaneous lymphoma group.
   
===Physical Examination===  
 
===Physical Examination===  
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An abdominal mass may be palpable and bowel loops may feel thickened. Additionally enlarged mesenteric lymph nodes may be palpable
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An abdominal mass may be palpable and bowel loops may feel thickened in alimentary lymphoma. Additionally enlarged mesenteric lymph nodes and enlarged abdominal organs may be palpable . Muffled heart sounds and a non-compressible thoracic region may be found in mediastinal lymphoma.
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Petechiae, anaemia and icterus may also be present in any form of lymphoma.
    
===Haematology and Biochemistry===
 
===Haematology and Biochemistry===
 
Haematological analysis should always be performed with suspected lymphoma for staging purposes and for the recording of base-line parameters prior to the initiation of any treatment to assess the severity of any future myelosuppression. Potential abnormalities for those patients with bone marrow involvement may include lymphocytosis, thrombocytopenia, neutropenia and the presence of immature lymphoid precursors
 
Haematological analysis should always be performed with suspected lymphoma for staging purposes and for the recording of base-line parameters prior to the initiation of any treatment to assess the severity of any future myelosuppression. Potential abnormalities for those patients with bone marrow involvement may include lymphocytosis, thrombocytopenia, neutropenia and the presence of immature lymphoid precursors
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Affected cats are not usually leukemic
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Affected cats are not usually leukemic.
 
On biochemistry abnormalities may include hypoproteinaemia, elevated hepatic enzymes and elevated Blood Urea Nitrogen /creatinine.
 
On biochemistry abnormalities may include hypoproteinaemia, elevated hepatic enzymes and elevated Blood Urea Nitrogen /creatinine.
  
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