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'''Opthalmic''': The initial signs are blephrospasm, increased lacrimation, photophobia and corneal oedema, with progression to retinal detachment, synechia formation, and cataracts. Chronic leptospirosis causes recurrent uvietis, typically signs develop 2-8 months after initial infection. Up to 67% of recurrent uveitis cases are due to leptospirosis.
 
'''Opthalmic''': The initial signs are blephrospasm, increased lacrimation, photophobia and corneal oedema, with progression to retinal detachment, synechia formation, and cataracts. Chronic leptospirosis causes recurrent uvietis, typically signs develop 2-8 months after initial infection. Up to 67% of recurrent uveitis cases are due to leptospirosis.
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'''Reproductive''': Leptospirosis can cause abortion, still birth or neonatal disease depending on the serovar and the stage of gestation when infected. Abortions are most frequently late term.
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'''Reproductive''': Leptospirosis can cause abortion, still birth or neonatal disease depending on the serovar and the stage of gestation when infected. Approximately 3-4% of equine abortions are caused by Leptospirosis, and are most frequently late term.
    
'''Renal''': leptospirosis rarely causes urologic signs including polyuria/polydipsia, azotaemia, pyuria and haematuria.
 
'''Renal''': leptospirosis rarely causes urologic signs including polyuria/polydipsia, azotaemia, pyuria and haematuria.
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A MAT or ELISA opn serum is a more sensitive diagnostic method. Paired titres 4 weeks apart are optimal.  
 
A MAT or ELISA opn serum is a more sensitive diagnostic method. Paired titres 4 weeks apart are optimal.  
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===Ultrasound===
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Abdominal ultrasound is useful in assessing the degree of damage in the hepatic and renal forms of the disease.
    
==Treatment==
 
==Treatment==
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