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'''Opthalmic''': The initial signs are blephrospasm, increased lacrimation, photophobia and corneal oedema, with progression to retinal detachment, synechia formation, and cataracts. Chronic leptospirosis causes recurrent uvietis, typically signs develop 2-8 months after initial infection. Up to 67% of recurrent uveitis cases are due to leptospirosis. It is not clear whether the recurrent uveitis is immune mediated or due to intraocular bacterial infection.   
 
'''Opthalmic''': The initial signs are blephrospasm, increased lacrimation, photophobia and corneal oedema, with progression to retinal detachment, synechia formation, and cataracts. Chronic leptospirosis causes recurrent uvietis, typically signs develop 2-8 months after initial infection. Up to 67% of recurrent uveitis cases are due to leptospirosis. It is not clear whether the recurrent uveitis is immune mediated or due to intraocular bacterial infection.   
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'''Reproductive''': Leptospirosis can cause abortion, still birth or neonatal disease depending on the serovar and the stage of gestation when infected. Approximately 3-4% of equine abortions are caused by Leptospirosis, and are most frequently late term.
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'''Reproductive''': Leptospirosis can cause placentitis, abortion, still birth or neonatal disease depending on the serovar and the stage of gestation when infected. Approximately 3-4% of equine abortions are caused by Leptospirosis, and are most frequently due to serovar Pomona, or occasionally Harjo. Abortion is usually late term, at 9 months of gestation.
    
'''Renal''': leptospirosis rarely causes urologic signs including polyuria/polydipsia, azotaemia, pyuria and haematuria.
 
'''Renal''': leptospirosis rarely causes urologic signs including polyuria/polydipsia, azotaemia, pyuria and haematuria.
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