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Anticoagulant Rodenticide Toxicity (view source)
Revision as of 12:51, 23 August 2010
, 12:51, 23 August 2010→Description
==Description==
==Description==
Anticoagulant rodenticides were first discovered during ingvestigations into mouldy sweet clover poisoning in cattle<sup>1</sup>. In this condition, naturally occuring coumarin in clover is converted by fungi to a toxic agent, dicumarol, which causes a haemorrhagic syndrome when ingested. Initially, warfarin was synthesised and used in this way for rodent control, but as rodents have developed a resistance to the substance new, second-generation anticoagulant rodenticides have been developed. These include difenacoum, bromadiolone, coumafuryl and brodifacoum amongst others, which may all causes toxicity in animals in the same way as warfarin.
One of the most common causes of an acquired coagulopathy
One of the most common causes of an acquired coagulopathy
in dogs is the accidental ingestion of an anticoagulant
in dogs is the accidental ingestion of an anticoagulant