Changes

==Diagnosis==

==Diagnosis==

Anticoagulant rodenticide toxicosis is usually diagnosed based on history of ingestion of the substance. Differential diagnoses when massive hemorrhage is encountered include disseminated intravascular coagulation, congenital factor deficiencies, von Willebrand’s disease, platelet deficiencies, and canine ehrlichiosis. A prolonged prothrombin, partial thromboplastin, or thrombin time in the presence of normal fibrinogen, fibrin degradation products, and platelet counts is strongly suggestive of anticoagulant rodenticide toxicosis, as is a positive therapeutic response to vitamin K1.  

 

Ideally, a diagnosis of anticoagulant rodenticide toxicosis should be made based on a history of ingestion of the substance. is usually diagnosed based on history of ingestion of the substance. Differential diagnoses when massive hemorrhage is encountered include disseminated intravascular coagulation, congenital factor deficiencies, von Willebrand’s disease, platelet deficiencies, and canine ehrlichiosis. A prolonged prothrombin, partial thromboplastin, or thrombin time in the presence of normal fibrinogen, fibrin degradation products, and platelet counts is strongly suggestive of anticoagulant rodenticide toxicosis, as is a positive therapeutic response to vitamin K1.  

===Clinical Signs===

===Clinical Signs===