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Coagulation Tests (view source)

Revision as of 14:44, 25 August 2010

211 bytes removed ,  14:44, 25 August 2010
→‎Fibrin Degradation Products
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===Fibrin Degradation Products===
 
===Fibrin Degradation Products===
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Fibrin Degradation Products
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A latex agglutination test is available for fibrin degradation products (FDP). To perform the test, serial dilutions of test s are prepared and Anti-FDP antibodies adsorbed onto latex particles are added. At a dilution, the test is positive if agglutination is seen, and the most dilute sample that agglutinates gives the overall result of the test. Normal values are between 1/4 and 1/16.
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Definition
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As a marker of fibrinolysis, fibrin degradation products (FDP), also known as fibrin split products (FSP), can be quantified by a test based on latex agglutination. The test uses antibodies to FSP which are measured using serial dilutions.
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Technique
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Serum is prepared in a series of dilutions (e.g., ½, ¼, 1/16). Latex particles onto which have been absorbed antibodies to FSP are added. If agglutination is seen, the test is positive at that dilution. The test is reported as the most dilute sample that agglutinates. The normal value is less than ¼ to ⅙.
   
Basic Science
 
Basic Science
  
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