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→Cyclosporine
cyclosporine is immuno-modulating rather than
cyclosporine is immuno-modulating rather than
immunosuppressive (Figure 2).
immunosuppressive (Figure 2).
Cyclosporine is administered for canine AD at a
Cyclosporine is administered for canine AD at a
dose of 5 mg/kg once daily. Controlled studies
dose of 5 mg/kg once daily. Controlled studies
management program can be more cost-effective
management program can be more cost-effective
than relying on it alone.
than relying on it alone.
The effect on intradermal testing and serology is
The effect on intradermal testing and serology is
thought to be minimal, although the data is sparse.
thought to be minimal, although the data is sparse.
Anecdotal data suggests that cyclosporine does
Anecdotal data suggests that cyclosporine does
not affect the response to ASIT any more than
not affect the response to ASIT any more than
glucocorticoids although controlled studies have
glucocorticoids
Cyclosporine is well tolerated by the majority of dogs.
Cyclosporine is well tolerated by the majority of dogs.
Transient anorexia and vomiting are the most likely
Transient anorexia and vomiting are the most likely
however, the risk appears to be very small and most
however, the risk appears to be very small and most
atopic dogs experience fewer secondary infections
atopic dogs experience fewer secondary infections
following treatment. Feline and human patients on
following treatment. Inhibition of
T-helper cell function and β-cell activation could
T-helper cell function and β-cell activation could
affect the response to vaccination. Some authors
affect the response to vaccination.-->steroids Some authors
advocate withdrawing treatment for up to two
advocate withdrawing treatment for up to two
weeks either side of vaccination, although this
weeks either side of vaccination, although this
will lead to worsening of the skin condition. The
will lead to worsening of the skin condition.
====Phytopica™====
====Phytopica™====