− | '''Tuberculoisis''' is a general term for diseases caused by the tuberculous group of bacteria, [[Mycobacteria spp.|Mycobacteria species]]. ''[[Mycobacterium tuberculosis]]'', ''[[Mycobacterium bovis]]'', ''[[Mycobacterium avium]]'' are host adapted to humans, cattle and birds respectively. All three types can produce disease in other species; ''Mycobacterium tiberculosis'' is the most host specific strain and rarely causes progresive disease in species other than humans, ''Mycobacterium bovis'' can affect a number of other species, see [[Bovine Tuberculosis]]. ''Mycobacterium avium'' is [[Avian Tuberculosis]]. | + | '''Tuberculoisis''' is a general term for diseases caused by the tuberculous group of bacteria, [[Mycobacteria spp.|Mycobacteria species]]. ''[[Mycobacterium tuberculosis]]'', ''[[Mycobacterium bovis]]'', ''[[Mycobacterium avium]]'' are host adapted to humans, cattle and birds respectively. All three types can produce disease in other species; ''Mycobacterium tiberculosis'' is the most host specific strain and rarely causes progresive disease in species other than humans, ''Mycobacterium bovis'' can affect a number of other species, see [[Bovine Tuberculosis]]. ''Mycobacterium avium'' is the only type that causes disease in birds but it can also affect mammalian species, see [[Avian Tuberculosis]]. |
− | Infection can be via inhalation of infective droplets, ingestion of contaminated feed or water, and occasionally via coitus or via milk. | + | Infection is usually via inhalation of infective droplets, but can aslo be by ingestion of contaminated feed or water, and occasionally via coitus or milk. The primary focus of infection is determined by the route of infection. Characteristic granulomatous tubercles develop. These become nectrotic, shedding the infective organism which disseminates to other body systems initiating secondary foci. |