*Dendritic cells present antigen to [[Lymphocytes#T cells|T cells]]
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Circulating [[Monocytes|monocytes]] differentiate to form immature dendritic cells called '''Langerhans Cells'''
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*Circulating [[Monocytes]] differentiate to form immature dendritic cells called '''Langerhans Cells'''
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Langerhans cells sample the tissue fluid by endocytosis:
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*Foreign organisms are internalised
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* Within the dendritic cells, antigen is digested to peptides
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* Some of the peptides formed bind to the cell’s [[MHC]] molecules
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*Langerhans cells sample the tissue fluid by endocytosis
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The Langerhans cells leave the epithelium and travel via the afferent lymph flow. They are now known as '''Veiled Cells'''. Veiled cells enter the paracortical region of the [[Lymph Nodes - Anatomy & Physiology|lymph node]] where they present antigen to the T cells. They are now known as '''Interdigitating Dendritic Cells'''.
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**Foreign organisms are internalised
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** Within the dendritic cells, antigen is digested to peptides
−
** Some of the peptides formed bind to the cell’s [[MHC]] molecules
−
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*The Langerhans cells leave the epithelium and travel via the afferent lymph. They are now called '''Veiled Cells'''
−
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*Veiled cells enter the paracortical region of the [[Lymph Nodes - Anatomy & Physiology|lymph node]] where they present antigen to [[Lymphocytes#T cells|T cells]]. They are now called '''Interdigitating Dendritic Cells'''