Cytotoxic T cells kill virus infected cells where the organisms are contained in the cell cytoplasm. Viruses are obligate intracellular pathogens that use the host cell machinery for pathogen protein synthesis; viral peptides associate with MHC class I and are expressed on the cell surface. [[Lymphocytes#Cytotoxic CD8+|CD8+ cytotoxic T-lymphocytes (CTL)]] recognise the antigen-MHC complex.
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*Cytotoxic T cells kill virus infected cells (''organisms in cytoplasm'')
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* Viruses are intracellular pathogens that use the host cell machinery for pathogen protein synthesis.
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** Viral peptides associate with MHC class I and are expressed on the cell surface.
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*** [[Lymphocytes#Cytotoxic CD8+|CD8+ cytotoxic T-lymphocytes (CTL)]] recognise the antigen-MHC complex.
* Cytotoxic T-cells secrete a pattern of cytokines similar to that of TH<sub>1</sub> cells.
* Cytotoxic T-cells secrete a pattern of cytokines similar to that of TH<sub>1</sub> cells.