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The clotting factors - factor VII, factor XI and factors II and X in the extrinsic, intrinsic and common pathways respectively are dependent on Vitamn K when activated by the coagulation cascade.
The clotting factors - factor VII, factor XI and factors II and X in the extrinsic, intrinsic and common pathways respectively are dependent on Vitamn K when activated by the coagulation cascade.
==Other Causes of Vitamin K deficiencies==
Malabsorption syndromes and sterilisation of the gastrointestinal tract by prolonged antibiotic usage will also result in the depletion of vitamin K-dependent clotting factors<sup>2</sup>. In herbivores, fungi growing on poorly prepared hay or silage containing sweet vernal grass or sweet clover may break down natural coumarins in the plants to form dicoumarol and cause poisoning.
==References==
==References==
Also see [[Anticoagulant Rodenticide Toxicity]]
Also see [[Anticoagulant Rodenticide Toxicity]]