Bleeding disorders may occur if platelets are deficient ('''thrombocytopaenia''') or if the platelets are unable to function adequately ('''thrombocytopathia'''). [[Immune Mediated Thrombocytopaenia|Immune-mediated thrombocytopaenia]] (ITP) is one common cause of thrombocytopaenia and this may be a primary or secondary disease. '''Thrombocytosis''' refers to an increase in the blood platelet concentration above the normal level.
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Thrombocytopaenia and thrombocytopathia lead to disorders of primary haemostasis but, in general, this is less serious than the disorders of secondary haemostasis caused by deficiencies in the [[Coagulation Factor Deficiency|coagulation factors]].