| When other, ‘’’non-feline, carnivores’’’ (such as dogs) or sheep consume tissue cysts or oocysts from cat faeces, ''Toxoplasma gondii'' initiates '''extraintestinal replication'''. This process is the same for all hosts, and does not vary with the form of the parasite ingested. '''Bradyzoites''' and '''sporozoites''', from cysts and oocysts respectively, are released in the intestine and infect the intestinal epithelium where they replicate - asexual reproduction by '''endodyogeny''' (budding) producing 8-16 '''tachyzoites'''. Tachyzoites are lunate in shape, about 6 microns in diameter and possess the ability to multiply in almost any cell type. The infected cell ruptures to release tachyzoites which then disseminate via blood and lymph to infect other tissues. Tachyzoites then replicate intracellularly and, if the cell does not burst, they eventually encyst and persist for the life of the host. Tissue cysts readily form in the CNS, muscles and visceral organs. | | When other, ‘’’non-feline, carnivores’’’ (such as dogs) or sheep consume tissue cysts or oocysts from cat faeces, ''Toxoplasma gondii'' initiates '''extraintestinal replication'''. This process is the same for all hosts, and does not vary with the form of the parasite ingested. '''Bradyzoites''' and '''sporozoites''', from cysts and oocysts respectively, are released in the intestine and infect the intestinal epithelium where they replicate - asexual reproduction by '''endodyogeny''' (budding) producing 8-16 '''tachyzoites'''. Tachyzoites are lunate in shape, about 6 microns in diameter and possess the ability to multiply in almost any cell type. The infected cell ruptures to release tachyzoites which then disseminate via blood and lymph to infect other tissues. Tachyzoites then replicate intracellularly and, if the cell does not burst, they eventually encyst and persist for the life of the host. Tissue cysts readily form in the CNS, muscles and visceral organs. |
| + | #The Center for Food Security and Public Health, Iowa State University, College of Veterinary Medicine (2005). ''Toxoplasmosis Factsheet'', available at [http://www.cfsph.iastate.edu www.cfsph.iastate.edu] |