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Renin Angiotensin Aldosterone System (view source)
Revision as of 10:14, 26 October 2010
, 10:14, 26 October 2010→The System
===The System===
===The System===
[[Image:raasflowdefap.jpg|right|thumb|250px|<small><center>The Mechanism Behind the RAAS </center></small>]]
[[Image:raasflowdefap.jpg|right|thumb|275px|<small><center>The Mechanism Behind the RAAS </center></small>]]
[[Image:raasflowsumap.jpg|right|thumb|250px|<small><center>Summary of the purpose of the RAAS</center></small>]]
[[Image:raasflowsumap.jpg|right|thumb|250px|<small><center>Summary of the purpose of the RAAS</center></small>]]
In the event of blood pressure dropping [[Kidney Endocrine Function - Anatomy & Physiology#Renin|Renin]] is secreted due to the decreased stretch of the [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Juxtaglomerular Cells|'''juxtaglomerular cells''']] and an increased sympathetic stimulation triggered by the decreased activation of arterial baroreceptors. This enzyme cleaves the alpha glycoprotein '''Angiotensinogen''' which is released from the [[Liver - Anatomy & Physiology|liver]]. This produces '''Angiotensin 1''' which is further converted by [[Angiotensin Converting Enzyme(ACE) - Renal Anatomy & Physiology|'''Angiotensin Converting Enzyme''' (ACE)]] to '''Angiotensin 2''' mainly in the lungs but to a much lesser extent locally in the kidneys. Angiotensin 2 then works to restore blood pressure. In this section we cover its effects on and through the kidneys.
In the event of blood pressure dropping [[Kidney Endocrine Function - Anatomy & Physiology#Renin|Renin]] is secreted due to the decreased stretch of the [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Juxtaglomerular Cells|'''juxtaglomerular cells''']] and an increased sympathetic stimulation triggered by the decreased activation of arterial baroreceptors. This enzyme cleaves the alpha glycoprotein '''Angiotensinogen''' which is released from the [[Liver - Anatomy & Physiology|liver]]. This produces '''Angiotensin 1''' which is further converted by [[Angiotensin Converting Enzyme(ACE) - Renal Anatomy & Physiology|'''Angiotensin Converting Enzyme''' (ACE)]] to '''Angiotensin 2''' mainly in the lungs but to a much lesser extent locally in the kidneys. Angiotensin 2 then works to restore blood pressure. In this section we cover its effects on and through the kidneys.