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*increased urea and creatinine, hyperkalaemia,  
 
*increased urea and creatinine, hyperkalaemia,  
 
===Ultrasonography===
 
===Ultrasonography===
*Accumulation of Calcium Oxalate Crystals in kidney result in renal hyperechogenicity upon ultrasound examination <ref>'''Textbook of Veterinary Internal Medicine''', (Seventh Edition), ''Ettinger and Feldman''; p1968 </ref>.
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*Accumulation of Calcium Oxalate Crystals in kidney result in renal hyperechogenicity upon ultrasound examination <ref name=''multiples''>'''Textbook of Veterinary Internal Medicine''', (Seventh Edition), ''Ettinger and Feldman''; p1968 </ref>.
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===Biopsy====
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*Needle or surgical wedge biopsy of kidney <ref name=''multiples''>'''Textbook of Veterinary Internal Medicine''', (Seventh Edition), ''Ettinger and Feldman''; p1968 </ref>.
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===Pathology===
 
===Pathology===
 
==Treatment==
 
==Treatment==
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* Ethanol
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*4-methylpyrazole
 
Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.<ref>'''Canine Medicine and Therapeutics''' (Fourth Edition, 1998),''Blackwell Science'', p1049 </ref>
 
Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.<ref>'''Canine Medicine and Therapeutics''' (Fourth Edition, 1998),''Blackwell Science'', p1049 </ref>
  
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