Changes

** Encoded by a gene on the X chromosome, rare deficiencies in FoxP3 are characterised by autoimmunity, primarily towards gut tissue, the thyroid, pancreative beta-cells and the skin. Sufferers are unable to produce regulatory T cells and the only known treatment is a bone marrow transplant from a MHC-identical sibling.

** Encoded by a gene on the X chromosome, rare deficiencies in FoxP3 are characterised by autoimmunity, primarily towards gut tissue, the thyroid, pancreative beta-cells and the skin. Sufferers are unable to produce regulatory T cells and the only known treatment is a bone marrow transplant from a MHC-identical sibling.

==[[Immune tolerance flashcards - Wikiblood|Immune tolerance flashcards]]==

==Test yourself with the Immunology Flashcards==

[[Immune tolerance flashcards - Wikiblood|Immune tolerance flashcards]]

[[Category:Immunology]]

[[Category:Immunology]]