Difference between revisions of "Phosphorus"
Jump to navigation
Jump to search
Fiorecastro (talk | contribs) |
|||
| (13 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
| − | |||
==Overview== | ==Overview== | ||
| − | Phosphorus is the third most | + | Phosphorus is the third most abundent intracellular ion: |
1. Potassium | 1. Potassium | ||
| Line 14: | Line 13: | ||
==Homeostasis== | ==Homeostasis== | ||
| − | Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via '' | + | Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via ''Passive diffusion'' and ''[[Calcium#Calcitriol (Active Vitamin D3)|Vitamin D]] mediated active transport''. |
| + | |||
| + | Phosphorus is excreted in the urine or saliva (particularly in ruminants). | ||
===Hormonal Regulation=== | ===Hormonal Regulation=== | ||
| + | |||
[[Calcium#Parathyroid Hormone (PTH)|'''PTH''']] | [[Calcium#Parathyroid Hormone (PTH)|'''PTH''']] | ||
| − | + | *Mobilises phosphorus from bone, acting to increase plasma concentration of P | |
| − | + | *Increases phosphorus loss in the urine and saliva, acting to decrease plasma concentration | |
| + | So ultimately, PTH acts to remove phosphorus from the body entirely. | ||
[[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']] | [[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']] | ||
| − | + | *Increases phosphorus absorbtion from the intestines | |
| − | |||
==Pathology== | ==Pathology== | ||
| Line 30: | Line 32: | ||
Diseases relating to phosphorus homeostasis include: | Diseases relating to phosphorus homeostasis include: | ||
| − | + | *[[Bones Metabolic - Pathology#Primary hyperparathyroidism |Primary and Secondary Hyperparathyroidism]] | |
| − | + | *[[Kidney Renal Failure - Pathology#Uraemia |Hyperphosphataemia]] | |
| − | + | *Hypophosphatemia | |
| − | |||
| − | |||
| + | ==Test yourself with the Phosphorus Homeostasis Flashcards== | ||
| + | [[Phosphorus_Homeostasis_Flash_Cards_- Anatomy & Physiology|Phosphorus Homeostasis Flashcards]] | ||
| − | |||
| − | |||
| − | |||
| − | |||
[[Category:Endocrine System - Anatomy & Physiology]] | [[Category:Endocrine System - Anatomy & Physiology]] | ||
[[Category:Electrolytes]] | [[Category:Electrolytes]] | ||
| − | [[Category:A&P | + | [[Category:To Do - A&P]] |
| − | |||
Revision as of 16:32, 5 January 2011
Overview
Phosphorus is the third most abundent intracellular ion:
1. Potassium
2. Magnesium
3. Phosphorus (as Phosphate)
Within the body it is found as Phosphate ions, or Phosphate within bone. The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.
Homeostasis
Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via Passive diffusion and Vitamin D mediated active transport.
Phosphorus is excreted in the urine or saliva (particularly in ruminants).
Hormonal Regulation
- Mobilises phosphorus from bone, acting to increase plasma concentration of P
- Increases phosphorus loss in the urine and saliva, acting to decrease plasma concentration
So ultimately, PTH acts to remove phosphorus from the body entirely.
- Increases phosphorus absorbtion from the intestines
Pathology
Diseases relating to phosphorus homeostasis include:
- Primary and Secondary Hyperparathyroidism
- Hyperphosphataemia
- Hypophosphatemia