Difference between revisions of "Immunoglobulin D"
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[[Image:LH IgD.png|thumb|250px|right|'''IgD''']] | [[Image:LH IgD.png|thumb|250px|right|'''IgD''']] | ||
[[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]] | [[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]] | ||
− | ''Shortened to IgD'' | + | ==Overview== |
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+ | ''Shortened to IgD'' | ||
IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted. | IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted. | ||
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==Structure== | ==Structure== | ||
− | IgD is Y-shaped. In rodents, it has two | + | IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds. |
==Function== | ==Function== | ||
− | IgD is only expressed in association with [[IgM]]. It is | + | IgD is only expressed in association with [[IgM]]. It is important in B-cell development. |
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==Links== | ==Links== | ||
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[[Immunoglobulin A|Immunoglobulin A]] | [[Immunoglobulin A|Immunoglobulin A]] | ||
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+ | [[Immunoglobulin D|Immunoglobulin D]] | ||
[[Immunoglobulin E|Immunoglobulin E]] | [[Immunoglobulin E|Immunoglobulin E]] | ||
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[[Immunoglobulin M|Immunoglobulin M]] | [[Immunoglobulin M|Immunoglobulin M]] | ||
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[[Category:Immunoglobulins]] | [[Category:Immunoglobulins]] | ||
− | [[Category: | + | [[Category:Image Review]] |
+ | [[Category:To Do - AimeeHicks]] |
Revision as of 14:39, 9 January 2011
Overview
Shortened to IgD
IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.
Structure
IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.
Function
IgD is only expressed in association with IgM. It is important in B-cell development.