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{{frontpage

|pagetitle =Brachyspira and Serpulina

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|pagebody =The ''Brachyspira'' and ''serpulina'' species are anaerobic, intestinal ''[[spirochaetes]]'', found in normal and diseased pigs.

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*Anaerobic, intestinal spirochaetes, found in normal and diseased pigs

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*Enterophogens of pigs

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*''B. hyodysenteriae, B. pilosicoli, B. innocens, Serpulina intermedia'' and ''S. murdochii'' occur in pigs

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*Carrier pigs shed ''B. hyodysenteriae'' for up to 3 months, acting as a source of infection for healthy pigs

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*Demonstrated in stained faecal smears or silver-stained histopathology sections

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*Cultured anaerobically on selective blood agar

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*Spirochaetes differentiated by pattern of haemolysis on blood agar as well as molecular techniques

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*Pathogenesis

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**Motility in mucous allows colonisation of pig intestine

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**Haemolytic and cytotoxic activiity important for virulence

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**Attachment of ''B. pilosicoli'' to epithelial cells of colonic mucosa disrupts their function and leads to their shedding and oedema

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[[Category:Spirochaetaceae]]

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[[Category:Spirochaetaceae~~]][[Category:Pig]]~~

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~~[[Category:To_Do_-_Bacteria~~]]

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Category:Brachyspira and Serpulina (view source)

Revision as of 18:57, 17 January 2011