Difference between revisions of "Category:Enteritis, Villus Atrophy"

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==Villus Atrophy==
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|pagetitle =Enteritis, Villus Atrophy
* Commonly seen in enteric disease.
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|pagebody = * Commonly seen in enteric disease.
 
* Occurs when more enterocytes are lost than are produced in the crypts.
 
* Occurs when more enterocytes are lost than are produced in the crypts.
 
* Causes  malabsorption of nutrients and water.
 
* Causes  malabsorption of nutrients and water.
* There are two main types of villus atrophy:
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* There are two main types of villus atrophy, with and without damage to the crypts.
 
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|contenttitle =Content
===Villus atrophy with intact/hypertrophic crypt glands===
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|contentbody =<big><b>
 
* Insult affects the villus enterocytes leading to increased loss.
 
** Under mild insult, villi may fully regenerate.
 
** Severe insult leads to immature cells on the villus.
 
*** Secrete water and electrolytes into lumen.
 
* Examples include:
 
** '''Rotavirus, Coronavirus'''
 
*** Infect villus enterocytes.
 
** '''Coccidia'''
 
*** Infect surface enterocytes.
 
** '''Nematodes'''
 
*** Abrase surface.
 
 
 
 
 
===Villus atrophy with damage to crypts===
 
 
* The primary insult is to crypt cells.
 
** Crypt cell death leads to dilated gland lumens (cysts).
 
** Production is impaired, eventually leading to insufficient cells for villi. 
 
* Enterocytes lost to lumen are replaced by increasingly immature cells.
 
** Gives rise to severe malabsorption.
 
* If damage is severe, erosions/ulcers may form which may eventually heal.
 
** Even if there are no ulcers, damage can be long-term
 
*** Causes long-term malabsorption.
 
* Examples include:
 
** '''Parvovirus'''
 
*** Target crypt cells.
 
** '''Lymphoma'''
 
*** Numerous neoplastic lymphocytes compress crypts.
 
** '''Cytotoxic chemicals'''
 
*** Dividing crypt cells are susceptible.
 
 
 
==Enteritis Particularly Associated with Villus Atrophy==
 
 
 
===[[Reoviridae#Rotaviruses|Rotavirus]]===
 
 
 
 
 
 
 
===[[Cryptosporidium|Cryptosporidium]]===
 
  
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<categorytree mode=pages>Enteritis, Villus Atrophy</categorytree>
  
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</b></big>
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|logo =path-logo.png
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[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]
 
[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

Latest revision as of 18:32, 15 February 2011

Enteritis, Villus Atrophy

* Commonly seen in enteric disease.

  • Occurs when more enterocytes are lost than are produced in the crypts.
  • Causes malabsorption of nutrients and water.
  • There are two main types of villus atrophy, with and without damage to the crypts.

Pages in category "Enteritis, Villus Atrophy"

The following 5 pages are in this category, out of 5 total.