Difference between revisions of "Swine Influenza"
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− | + | ===Subtypes=== | |
+ | *Avian-like H1 and human-like H3 strains vary in virulence | ||
+ | ===Pathogenesis=== | ||
+ | *Necrotising bronchiolitis with catarrhal pus | ||
+ | *Barking cough | ||
+ | *Interstitial pneumonia giving consolidation of the lungs and a 'meaty' appearance | ||
+ | *Often associated with bacteria, mycoplasma or immunosuppressive viruses (such as PRRS) | ||
+ | *The virus recycles on farms as litters outgrow maternal antibody at 12 weeks of age | ||
− | + | ===Diagnosis=== | |
+ | *Clinical pneumonia is always suspect | ||
+ | *Serology: retrospective diagnosis by HI | ||
+ | ===Control=== | ||
+ | *Isolation of premises | ||
+ | *All-in/all-out systems | ||
+ | *Vaccination is not licensed in the UK | ||
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− | + | *Caused by [[Orthomyxoviridae]] | |
+ | *[[Rhinitis|Rhinitis]], may progress to [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | ||
+ | *Clinical signs: pyrexia, lethargy, skin erythema, anorexia, severe cough and sneezing, dyspnoea, conjunctivitis, pregnant sows may abort | ||
+ | *Grossly: | ||
+ | **[[Tracheitis|Tracheo]][[Bronchitis#Infectious causes of bronchitis or bronchiolitis|bronchitis]], airway obstruction -> [[Lungs Ventilation - Pathology#Atelectasis (Collapse)|atelectasis]] | ||
+ | **[[Pleural Cavity & Membranes Inflammatory - Pathology|Pleura]] normal or covered with serous or serofibrinous exudate | ||
+ | **[[Pleural Cavity & Membranes Inflammatory - Pathology|Pleural cavity]] filled with excess fluid | ||
+ | **Lung lesions | ||
+ | ***Clear demarcation of lesions in cranial and middle lobes | ||
+ | ***[[Lungs Inflammatory - Pathology#Interstitial pneumonia|Interstitial pneumonia]] | ||
+ | *Histologically: | ||
+ | **Acute inflammation of mucosa of trachea and bronchi | ||
+ | *Zoonotic | ||
+ | *Circumstantial evidence of mutation from human strain | ||
+ | *Migrating [[Respiratory Parasitic Infections - Pathology#Ascaris suum|ascarids]] thought to precipitate the disease, reservoir of infection in earthworms containing infected lungworm larvae | ||
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− | + | [[Category:Orthomyxoviridae]][[Category:Pig Viruses]][[Category:Respiratory Diseases - Pig]] | |
− | + | [[Category:To_Do_-_Clinical/Viruses]] | |
− | + | [[Category:Respiratory_Viral_Infections]] | |
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Revision as of 16:13, 19 February 2011
This article is still under construction. |
Subtypes
- Avian-like H1 and human-like H3 strains vary in virulence
Pathogenesis
- Necrotising bronchiolitis with catarrhal pus
- Barking cough
- Interstitial pneumonia giving consolidation of the lungs and a 'meaty' appearance
- Often associated with bacteria, mycoplasma or immunosuppressive viruses (such as PRRS)
- The virus recycles on farms as litters outgrow maternal antibody at 12 weeks of age
Diagnosis
- Clinical pneumonia is always suspect
- Serology: retrospective diagnosis by HI
Control
- Isolation of premises
- All-in/all-out systems
- Vaccination is not licensed in the UK
- Caused by Orthomyxoviridae
- Rhinitis, may progress to pneumonia
- Clinical signs: pyrexia, lethargy, skin erythema, anorexia, severe cough and sneezing, dyspnoea, conjunctivitis, pregnant sows may abort
- Grossly:
- Tracheobronchitis, airway obstruction -> atelectasis
- Pleura normal or covered with serous or serofibrinous exudate
- Pleural cavity filled with excess fluid
- Lung lesions
- Clear demarcation of lesions in cranial and middle lobes
- Interstitial pneumonia
- Histologically:
- Acute inflammation of mucosa of trachea and bronchi
- Zoonotic
- Circumstantial evidence of mutation from human strain
- Migrating ascarids thought to precipitate the disease, reservoir of infection in earthworms containing infected lungworm larvae