Difference between revisions of "Parathyroid Glands - Pathology"

Revision as of 14:05, 21 February 2011

Anatomy and Physiology of the Parathyroid glands can be found here.

Non-endocrine tumours may be capable of secreting hormones, or hormone-like factors.
- A parathormone-like substance may be secreted in such a manner.

Malignant tumours of the anal sac apocrine glands can produce PTH-related peptide (PTHrp).
- This induces a pseudo-hyperparathyroidism and hypercalcaemia.

Some other carcinomas may also be capable of causing pseudo-hyperparathyroidism.

@@ Line 1: / Line 1: @@
-#REDIRECT[[:Category:Parathyroid Glands - Pathology]]
+==Anatomy and Physiology==
+Anatomy and Physiology of the Parathyroid glands can be found [[Parathyroid Glands - Anatomy & Physiology|here]].
+==[[Hypercalcaemia]]==
+==[[Hypocalcaemia]]==
+==[[Hyperparathyroidism]]==
+==Pseudo-Hyperparathyroidism==
+* Non-endocrine tumours may be capable of secreting hormones, or hormone-like factors.
+** A parathormone-like substance may be secreted in such a manner.
+===Apocrine Gland Adenocarcinoma===
+* Malignant tumours of the anal sac apocrine glands can produce PTH-related peptide (PTHrp).
+** This induces a pseudo-hyperparathyroidism and hypercalcaemia.
+===[[Lymph Nodes - Pathology#Neoplasia|Lymphosarcoma]]===
+* 10 to 40% of cases in dogs may cause a pseudo-hyperparathyroidism.
+===Other Carcinomas===
+Some other carcinomas may also be capable of causing pseudo-hyperparathyroidism.
+[[Category:Parathyroid Glands - Pathology]]
+==[[Hypoparathyroidism]]==
+* Hypoparathyroidism may result from primary gland hypofunction.
+** Gland hypofunction occurs due to:
+**# Destruction of secretory cells by a disease process.
+**#* For example, this may be immune mediated, or another inflammatory cause.
+**# A biochemical defect in synthetic pathway of the hormone.
+**#* These are usually genetic aberrations.
+**#* Defects in synthesis are not commonly identified in the veterinary species.
+[[Category:Parathyroid Glands - Pathology]]