Changes

===Loss of Blood Supply===

===Loss of Blood Supply===

* Necrosis due to interuption of blood supply to a portion of tissue is known as '''ischaemic necrosis''', or [[Ischaemia and Infarction - Pathology#Infarction|'''infarction''']].

* Necrosis due to interuption of blood supply to a portion of tissue is known as '''ischaemic necrosis''', or [[Infarction|'''infarction''']].

* The effects of [[Ischaemia and Infarction - Pathology#Ischaemia|ischaemia]] on a tissue vary according to:

* The effects of [[Ischaemia|ischaemia]] on a tissue vary according to:

** The tissue affected.

** The tissue affected.

*** Some tissues are more susceptible than others.

*** Some tissues are more susceptible than others.

* Tissue [[Ischaemia and Infarction - Pathology#Ischaemia|ischamia]] can be brought about in three ways:

* Tissue [[Ischaemia|ischamia]] can be brought about in three ways:

** Compression of the blood vessel.

** Compression of the blood vessel.

** Narrowing of the lumen.

** Narrowing of the lumen.

*** Commonly seen following a septicaemic condition when an embolus blocks the blood supply.

*** Commonly seen following a septicaemic condition when an embolus blocks the blood supply.

**** When seen in calves, the possibility of [[Salmonellosis|salmonellosis]] must be kept in mind.

**** When seen in calves, the possibility of [[Salmonellosis|salmonellosis]] must be kept in mind.

*** Other causes are frostbite and [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]].

*** Other causes are frostbite and [[Ergot Poisoning|ergot poisoning]].

==Calcification==

==Calcification==