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==Introduction==
==Introduction==
* '''Necrosis''' means the death of cells within the living body.
* '''Necrosis''' means the death of cells within the living body.
===Loss of Blood Supply===
===Loss of Blood Supply===
* Necrosis due to interuption of blood supply to a portion of tissue is known as '''ischaemic necrosis''', or [[Ischaemia and Infarction - Pathology#Infarction|'''infarction''']].
* Necrosis due to interuption of blood supply to a portion of tissue is known as '''ischaemic necrosis''', or [[Infarction|'''infarction''']].
* The effects of [[Ischaemia and Infarction - Pathology#Ischaemia|ischaemia]] on a tissue vary according to:
* The effects of [[Ischaemia|ischaemia]] on a tissue vary according to:
** The tissue affected.
** The tissue affected.
*** Some tissues are more susceptible than others.
*** Some tissues are more susceptible than others.
* Tissue [[Ischaemia and Infarction - Pathology#Ischaemia|ischamia]] can be brought about in three ways:
* Tissue [[Ischaemia|ischamia]] can be brought about in three ways:
** Compression of the blood vessel.
** Compression of the blood vessel.
** Narrowing of the lumen.
** Narrowing of the lumen.
*** Commonly seen following a septicaemic condition when an embolus blocks the blood supply.
*** Commonly seen following a septicaemic condition when an embolus blocks the blood supply.
**** When seen in calves, the possibility of [[Salmonellosis|salmonellosis]] must be kept in mind.
**** When seen in calves, the possibility of [[Salmonellosis|salmonellosis]] must be kept in mind.
*** Other causes are frostbite and [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]].
*** Other causes are frostbite and [[Ergot Poisoning|ergot poisoning]].
==Calcification==
==Calcification==
** The cell breaks up into fragments that are engulfed by neighbouring cells or local macrophages.
** The cell breaks up into fragments that are engulfed by neighbouring cells or local macrophages.
*** Their remnants can be seen in the neighbouring cells’ cytoplasm.
*** Their remnants can be seen in the neighbouring cells’ cytoplasm.
[[Category:General Pathology]]