Difference between revisions of "Hypervitaminosis A"

Revision as of 18:55, 27 February 2011

Hypervitaminosis A (Image sourced from Bristol Biomed Image Archive with permission)

Main lesions:
- Injury to growth cartilage -> premature closure of growth plate
- Osteoporosis
- Exostoses
- Osteophyte formation in prolonged exposure
In cats fed bovine liver for prolonged periods
- Rich in vitamin A in grazing animals
- Vertebrae fuse with each other due to bone proliferation - cervical spondylosis (ankylosing exostosis of the vertebral column), especially in the neck
Can also be teratogenic, especially in pigs (cleft plate and abortions)

@@ Line 1: / Line 1: @@
-bones
 [[Image:Hypervitaminosis A.jpg|right|thumb|100px|<small><center>Hypervitaminosis A (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 *Main lesions:
 **Injury to growth cartilage -> [[Bones - Anatomy & Physiology|premature closure of growth plate]]
-**[[Osteoporosis|Osteoporosis]]
+**[[Bones Degenerative - Pathology#Osteoporosis (Atrophy)|Osteoporosis]]
 **'''Exostoses'''
 **[[Musculoskeletal Terminology - Pathology|Osteophyte]] formation in prolonged exposure
@@ Line 11: / Line 10: @@
 *Can also be teratogenic, especially in pigs ([[Cleft Palate|cleft plate]] and abortions)
-joints
-*May cause spondylosis of cervical vertebrae
-*Mainly on dorsolateral surface
-*Also in elbow and shoulder joints -> fixation of joint
-*May resolve with changes of diet
-[[Category:Joints - Degenerative Pathology]]
 [[Category:Bones - Metabolic Pathology]]
 [[Category:Toxicology]]