Difference between revisions of "Arthritis Classification"
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(Created page with "[[Image:Cattle fibrinopurulent arthritis.jpg|right|thumb|100px|<small><center>Fibrinopurulent arthritis in cattle (Image sourced from Bristol Biomed Image Archive with permission...") |
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**Foreign material (urate crystals = gout) | **Foreign material (urate crystals = gout) | ||
**Immune-mediated disease | **Immune-mediated disease | ||
+ | |||
+ | [[Category:Arthritis]] | ||
+ | ==Infectious arthritis== | ||
+ | |||
+ | *'''Bacterial arthritis''' | ||
+ | **Most common in food animals, especially young | ||
+ | **Portals of entry include: | ||
+ | ***Navel and GI tract -> bacteraemia | ||
+ | ***Haematogenously -> polyarthritis | ||
+ | ***Traumatic inoculation | ||
+ | ***Extension from bone or periarticular soft tissue | ||
+ | |||
+ | *'''Viral arthritis''' | ||
+ | **Progressive inflammatory and degenerative joint disease | ||
+ | **Synovitis with cartilage destruction | ||
+ | **Chronic mononuclear inflammatory reactions | ||
+ | |||
+ | |||
+ | ===In Sheep=== | ||
+ | |||
+ | *[[Retroviridae|'''Maedi visna virus''']] | ||
+ | *Bacterial infections mostly affects lambs except for Mycoplasmal artheritis | ||
+ | *[[Erysipelothrix rhusiopathiae|'''''Erysipelothrix rhusiopathiae''''']] | ||
+ | |||
+ | *'''''[[Corynebacterium pyogenes]]''''' | ||
+ | |||
+ | *[[:Category:Streptococcus species|'''''Streptococcus'' spp.''']] | ||
+ | |||
+ | *[[:Category:Staphylococcus species|'''''Staphylococci''''']] | ||
+ | |||
+ | *[[:Category:Chlamydophila species|'''''Chlamydia sp.''''']] | ||
+ | |||
+ | ===In Pigs=== | ||
+ | |||
+ | *[[Erysipelas - Pig|'''''Erysipelothrix rhusiopathiae''''']] | ||
+ | |||
+ | *'''''[[Corynebacterium pyogenes]]''''' and [[:Category:Staphylococcus species|'''''Staphylococci''''']] | ||
+ | |||
+ | *'''''[[Haemophilus suis]]'' and ''[[Haemophilus parasuis]]''''' | ||
+ | |||
+ | *'''''[[Mycoplasma hyosynoviae]]'' and ''M. hyorhinis''''' | ||
+ | |||
+ | ===In Cattle=== | ||
+ | |||
+ | *Neonatal polyarthritis by: | ||
+ | **[[:Category:Streptococcus species|'''''Streptococcus'' spp.''']] | ||
+ | ***Via umbilicus | ||
+ | ***Also involves eyes and meninges | ||
+ | **[[Escherichia coli|'''''Coliforms''''']] | ||
+ | ***Localises in joints and meninges in severe non-fatal neonatal colibacillosis | ||
+ | ***May remain as chronic arthritis in larger joints | ||
+ | *Infections at any age: | ||
+ | **'''''[[Corynebacterium pyogenes]]''''' | ||
+ | ***Suppurative arthrtis | ||
+ | ***Often due to pebetrating wound into or close to joints | ||
+ | **[[:Category:Mycoplasmas|'''''Mycoplasma spp.''''']] | ||
+ | ***May be respinsible for some chronic cases but difficult to prove as hard to isolate | ||
+ | ***Fibrinous polyarthritis | ||
+ | **[[:Category:Chlamydophila species|'''''Chlamydia sp.''''']] | ||
+ | ***Severe disease in young calves | ||
+ | ***High mortality | ||
+ | ***Can be seen in smears of synovial fluid from swollen joints | ||
+ | ***Oedematous and hyperaemic surrounding tissue | ||
+ | ***Possibly due to intrauterine infection | ||
+ | **'''''[[Brucella abortus]]''''' | ||
+ | ***Uncommonly localises in joints | ||
+ | ***Usually in '''carpal bursitis (hygroma) in cattle and bursitis in horses''' | ||
+ | |||
+ | ===In Horses=== | ||
+ | |||
+ | *Arthritis can occur following neonatal infections by: | ||
+ | **'''''[[Actinobacillus equuli]]''''' | ||
+ | **[[:Category:Streptococcus species|'''''Streptococcus'' spp.''']] | ||
+ | **[[Escherichia coli|'''''Coliforms''''']] | ||
+ | **[[Salmonella|'''''Salmonella''''']] | ||
+ | |||
+ | |||
+ | |||
+ | ===In Goats=== | ||
+ | |||
+ | *[[Caprine Arthrirtis Encephalitis Virus]] | ||
+ | |||
+ | ===In Dogs=== | ||
+ | |||
+ | *[[:Category:Staphylococcus species|'''''Staphylococci''''']] | ||
+ | **May cause '''discospondylitis''' | ||
+ | **Destructive inflammatory lesion | ||
+ | **Bacterial localise in ''[[Joints - Anatomy & Physiology#Fibrocartilagenous joints|''annulus fibrosis'']] -> may spread to local bone | ||
+ | |||
[[Category:Arthritis]] | [[Category:Arthritis]] |
Revision as of 16:16, 3 March 2011
- Inflammation of intra-articular structures
- In farm animals usually due to infection
- In small animals usually due to non-infectious causes
- Classification:
- According to number of joints involved - polyarthritis
- According to type of inflammatory exudate
- Serous
- Increased synovial fluid production
- Resolves if uncomplicated
- Fibrinous
- Early stages:
- Increased and more opaque synovial exudate
- Enlarged hyperaemic villi
- Small haemorrhages in synovial membrane
- Later stages:
- Less exudate
- Thickend synovial connective tissue
- Marked villi proliferation (branching in microscopic preparations)
- Proliferated synovial tissue -> peripheral fibrous tissue attempting repair across defective surface = pannus
- Mild cases resolve
- More severe cases - residual inflammation remains
- Most severe cases - organising fibrosis +/- ankylosis
- Early stages:
- Purulent
- Usually from haemoatogenous spread e.g. neonatal navel ill
- May extend from adjacent abscesses
- More destructive
- Erosion of articular surfaces to underlying bone
- Forms abscesses
- Possible fistulation to the skin
- Serous
- Caused by:
- Trauma
- Infectious organisms (e.g. bacteria, viruses)
- Foreign material (urate crystals = gout)
- Immune-mediated disease
Infectious arthritis
- Bacterial arthritis
- Most common in food animals, especially young
- Portals of entry include:
- Navel and GI tract -> bacteraemia
- Haematogenously -> polyarthritis
- Traumatic inoculation
- Extension from bone or periarticular soft tissue
- Viral arthritis
- Progressive inflammatory and degenerative joint disease
- Synovitis with cartilage destruction
- Chronic mononuclear inflammatory reactions
In Sheep
- Maedi visna virus
- Bacterial infections mostly affects lambs except for Mycoplasmal artheritis
- Erysipelothrix rhusiopathiae
In Pigs
- Mycoplasma hyosynoviae and M. hyorhinis
In Cattle
- Neonatal polyarthritis by:
- Streptococcus spp.
- Via umbilicus
- Also involves eyes and meninges
- Coliforms
- Localises in joints and meninges in severe non-fatal neonatal colibacillosis
- May remain as chronic arthritis in larger joints
- Streptococcus spp.
- Infections at any age:
- Corynebacterium pyogenes
- Suppurative arthrtis
- Often due to pebetrating wound into or close to joints
- Mycoplasma spp.
- May be respinsible for some chronic cases but difficult to prove as hard to isolate
- Fibrinous polyarthritis
- Chlamydia sp.
- Severe disease in young calves
- High mortality
- Can be seen in smears of synovial fluid from swollen joints
- Oedematous and hyperaemic surrounding tissue
- Possibly due to intrauterine infection
- Brucella abortus
- Uncommonly localises in joints
- Usually in carpal bursitis (hygroma) in cattle and bursitis in horses
- Corynebacterium pyogenes
In Horses
- Arthritis can occur following neonatal infections by:
In Goats
In Dogs
- Staphylococci
- May cause discospondylitis
- Destructive inflammatory lesion
- Bacterial localise in annulus fibrosis -> may spread to local bone