Difference between revisions of "Muscles Degenerative - Pathology"
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| − | # | + | ==Degeneration== |
| + | [[Image:Degenerate muscle fibres.jpg|right|thumb|100px|<small><center>Degenerate muscle fibres (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]] | ||
| + | |||
| + | *Different types of degeneration | ||
| + | *May, or may not, be reversible | ||
| + | *Cloudy swelling, hydropic, vacuolar, granular and fatty change | ||
| + | *Occur following many different types of insult and are usually '''segmental''' | ||
| + | *If regeneration does not occur after formation of small vacuoles, [[Muscles Degenerative - Pathology#Necrosis|necrosis]] follows | ||
| + | **Vacuolation -> floccular degeneration -> granular degeneration -> [[Hyaline Degeneration|hyaline]] and [[Zenker Degeneration - Pathology|Zenker’s degeneration]] | ||
| + | *[[Hydropic Degeneration#Vacuolar Degeneration|'''Vacuolar degeneration''']]: | ||
| + | **Due to swelling of organelles or due to glycogen or fat accumulation | ||
| + | **May be caused by hypokalaemia, hyperkalaemia or necrosis | ||
| + | *Histologically: | ||
| + | **Swollen | ||
| + | **Hypereosinophilic | ||
| + | **Lost cross striations | ||
| + | ===[[Muscle Calcification]]=== | ||
| + | ===[[Muscle Ossification]]=== | ||
| + | ===[[Muscle Pigmentation]]=== | ||
| + | |||
| + | |||
| + | ==Nutritional myopathy== | ||
| + | |||
| + | ===[[White Muscle Disease|White muscle disease]]=== | ||
| + | |||
| + | |||
| + | ==Exertional myopathies== | ||
| + | |||
| + | *Caused by intensive and exhaustive activity of major muscle masses | ||
| + | *Glycogen used up -> local heat and lactic acid -> muscle degeneration | ||
| + | *Other forms include '''capture myopathy''', racing greyhounds, sheep chased by dogs | ||
| + | |||
| + | |||
| + | ===[[Equine Rhabdomyolysis]]=== | ||
| + | |||
| + | ===[[Porcine Stress Syndrome]]=== | ||
| + | |||
| + | ==Neuromuscular junction diseases== | ||
| + | |||
| + | ===Aquired myasthenia gravis=== | ||
| + | |||
| + | *See [[Myasthenia Gravis|congenital MG]] | ||
| + | |||
| + | |||
| + | ===[[Botulism]]=== | ||
| + | |||
| + | ==Circulatory disturbances== | ||
| + | |||
| + | ===[[Muscle Congestion]]=== | ||
| + | |||
| + | |||
| + | ===[[Muscle Ischaemia]]=== | ||
| + | |||
| + | |||
| + | ==[[Muscle Trauma]]== | ||
| + | |||
| + | |||
| + | |||
| + | [[Category:Musculoskeletal System - Pathology]] | ||
Revision as of 18:12, 3 March 2011
Degeneration
- Different types of degeneration
- May, or may not, be reversible
- Cloudy swelling, hydropic, vacuolar, granular and fatty change
- Occur following many different types of insult and are usually segmental
- If regeneration does not occur after formation of small vacuoles, necrosis follows
- Vacuolation -> floccular degeneration -> granular degeneration -> hyaline and Zenker’s degeneration
- Vacuolar degeneration:
- Due to swelling of organelles or due to glycogen or fat accumulation
- May be caused by hypokalaemia, hyperkalaemia or necrosis
- Histologically:
- Swollen
- Hypereosinophilic
- Lost cross striations
Muscle Calcification
Muscle Ossification
Muscle Pigmentation
Nutritional myopathy
White muscle disease
Exertional myopathies
- Caused by intensive and exhaustive activity of major muscle masses
- Glycogen used up -> local heat and lactic acid -> muscle degeneration
- Other forms include capture myopathy, racing greyhounds, sheep chased by dogs
Equine Rhabdomyolysis
Porcine Stress Syndrome
Neuromuscular junction diseases
Aquired myasthenia gravis
- See congenital MG