Difference between revisions of "Equine Rhabdomyolysis"
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(Created page with "*'''Azoturia''' (Monday morning disease) **Acute **Due to exercise following a prolonged period of rest **Clincal signs: ***Unable to move ***Sweating ***Tremors ***Swollen and h...") |
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***Salmon pink muscles -> dark, moist, swollen +/- pale streaks | ***Salmon pink muscles -> dark, moist, swollen +/- pale streaks | ||
**Histologically: | **Histologically: | ||
| − | ***Segmental myofibre [[ | + | ***Segmental myofibre [[Muscle Necrosis|necrosis]] |
****Multifocal and monophasic, but may be multiphasic if repeated bouts | ****Multifocal and monophasic, but may be multiphasic if repeated bouts | ||
***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease | ***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease | ||
Revision as of 18:30, 3 March 2011
- Azoturia (Monday morning disease)
- Acute
- Due to exercise following a prolonged period of rest
- Clincal signs:
- Unable to move
- Sweating
- Tremors
- Swollen and hard lumbar, gluteal and femoral muscles
- Myoglobin leaks from muscle cells -> leaks into urine -> urine is dark red/brown (myoglobinuria) -> damages renal tubules
- Grossly:
- Salmon pink muscles -> dark, moist, swollen +/- pale streaks
- Histologically:
- Segmental myofibre necrosis
- Multifocal and monophasic, but may be multiphasic if repeated bouts
- Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
- Minor inflammatory reaction and calcification
- Segmental myofibre necrosis
- Tying-up
- Similar to azoturia but much milder
- Grossly - normal muscle
- Histologically - same as azoturia