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**In cattle, vertical transmission occurs
 
**In cattle, vertical transmission occurs
 
***Post-natal infection occurs but is less common
 
***Post-natal infection occurs but is less common
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*''Neospora caninum'' in [[Parasitic Myositis#Protozoa|myositis]]
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'''Pathogenesis'''
 
'''Pathogenesis'''
*Dogs
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**Occurs mainly in puppies
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**Causes ascending paralysis, especially of hind limbs, with muscle wasting
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**Causes sudden collapse due to myocarditis
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**More than 1 puppy in a litter may be affected, although this may not occur simultaneously
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**Successive litters affected
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*Cattle
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<big>
**Commonest cause of infectious abortion in dairy cattle
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'''[[Neosporosis - Dog|Dog Neosporosis]]
**Congenitally infected calves can have encephalomyelitis and paresis
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**Abortion usually occurs between 5-7 months of gestation but can occur as early as 3 months
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'''[[Neosporosis - Cattle|Cattle Neosporosis]]
**No other clinical signs in the cow
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**Repeat abortions possible in same cow (persistently infected)
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'''[[Neosporosis - Horse|Horse Neosporosis]]
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</big>
   −
*Horses
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**Myeloencephalitis
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**Transplacental infection occurs
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**Disease only diagnosed in USA
     −
*''Neospora caninum'' in [[Muscles Inflammatory - Pathology#Protozoa|myositis]]
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*''N. caninum''
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**Necrotising inflammation of muscles
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**Myositis more severe than in toxoplasmosis
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'''Prevention and Control'''
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''N. caninum'' - A disease of cattle with late abortion of mummified or autolysed foetus. May also get foetal malformation, e.g. arthrogryposis.
*Do not allow dogs access to calving cows, placental membranes and aborted or dead calves
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*Do not allow dogs to defecate in cattle feeding areas
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==Test yourself with the Tissue Cyst Forming Coccidian Flashcards==
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*Identify and cull seropositive cattle, or do not breed from them or their progeny
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[[Tissue_Cyst_Forming_Coccidian_Flashcards|Tissue Cyst Forming Coccidian Flashcards]]
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*Select seronegative cattle for breeding
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[[Category:Tissue Cyst Forming Coccidia]]
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*Vaccinate
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[[Category:To_Do_-_Parasites]]
**Only in the USA
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**Neoguard or Intervet
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**Killed protozoal vaccine for healthy, pregnant cows
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**Dosed in first 3 weeks of pregnancy and then every 3-4 weeks during gestation
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**Revaccination with 2 doses during each subsequent pregnancy[[Category:Tissue Cyst Foming Coccidia]]
 
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