Difference between revisions of "CNS Inflammation - Pathology"
Jump to navigation
Jump to search
(Redirected page to Category:Central Nervous System - Inflammatory Pathology) |
|||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
| − | + | [[Central Nervous System Inflammation Overview]] | |
| + | |||
| + | |||
| + | |||
| + | [[Central Nervous System Infectious Inflammation]] | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | ==[[:Category:CNS Non-Infectious Inflammatory Diseases]]== | ||
| + | |||
| + | ===[[Granulomatous Meningoencephalitis]]=== | ||
| + | (GME) | ||
| + | * An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]] | ||
| + | * May occur as: | ||
| + | ** A disseminated disease | ||
| + | ** A focal mass lesion | ||
| + | ** A primary occular disease | ||
| + | * Brainstem signs are common, although the forebrain is primarily affected. | ||
| + | * May be incorrectly diagnosed as lymphoma. | ||
| + | * Changes are apparent in the CSF. | ||
| + | ** There is usually a mononucloear pleocytosis. | ||
| + | ** Sometimes only protein is elveated. | ||
| + | * Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging. | ||
| + | ** However, biopsy is required for a definative diagnosis. | ||
| + | * Life span is between 6 months and 1 year from diagnosis. | ||
| + | |||
| + | ====Treatment==== | ||
| + | |||
| + | * Immunosuppression: | ||
| + | ** Corticosteroids | ||
| + | ** Azathioprine | ||
| + | ** Cycophosphamide | ||
| + | * Surgery | ||
| + | ** This is only appropriate if there is a focal mass. | ||
| + | * Radiation therapy. | ||
| + | |||
| + | [[Necrotising Meningoencephalitis]] | ||
| + | |||
| + | [[:Category:CNS Non-Infectious Inflammatory Diseases]] | ||
| + | |||
| + | |||
| + | ===Pug Encephalitis=== | ||
| + | |||
| + | * A [[CNS Idiopathic Conditions - Pathology|CNS idiopathic condition]] | ||
| + | * Affects pugs. | ||
| + | ** Similar conditions are seen in yorkshire and maltese terriers. | ||
| + | * Officially known as necrotising meningoencephalitis of small dogs. | ||
| + | * Characterised by histological forebrain inflammation and necrosis. | ||
| + | * The disease is uniformly fatal. | ||
| + | ** Corticosterid treatment has no effect. | ||
| + | |||
| + | |||
| + | [:Category:CNS Non-Infectious Inflammatory Diseases]] | ||
Revision as of 12:52, 8 March 2011
Central Nervous System Inflammation Overview
Central Nervous System Infectious Inflammation
Category:CNS Non-Infectious Inflammatory Diseases
Granulomatous Meningoencephalitis
(GME)
- An idiopathic CNS conditon
- May occur as:
- A disseminated disease
- A focal mass lesion
- A primary occular disease
- Brainstem signs are common, although the forebrain is primarily affected.
- May be incorrectly diagnosed as lymphoma.
- Changes are apparent in the CSF.
- There is usually a mononucloear pleocytosis.
- Sometimes only protein is elveated.
- Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
- However, biopsy is required for a definative diagnosis.
- Life span is between 6 months and 1 year from diagnosis.
Treatment
- Immunosuppression:
- Corticosteroids
- Azathioprine
- Cycophosphamide
- Surgery
- This is only appropriate if there is a focal mass.
- Radiation therapy.
Necrotising Meningoencephalitis
Category:CNS Non-Infectious Inflammatory Diseases
Pug Encephalitis
- A CNS idiopathic condition
- Affects pugs.
- Similar conditions are seen in yorkshire and maltese terriers.
- Officially known as necrotising meningoencephalitis of small dogs.
- Characterised by histological forebrain inflammation and necrosis.
- The disease is uniformly fatal.
- Corticosterid treatment has no effect.
[:Category:CNS Non-Infectious Inflammatory Diseases]]