Difference between revisions of "Cognitive Dysfunction Syndrome"
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*** Nicergoline | *** Nicergoline | ||
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[[Category:Central Nervous System - Degenerative Pathology]] | [[Category:Central Nervous System - Degenerative Pathology]] |
Revision as of 14:13, 8 March 2011
(CDS)
- CDS causes signs of senility.
- Increasing numbers of dogs and cats are suffering from CDS.
- Prevalence is similar to that seen in humans: an 85 year-old human is roughly equivalent to a 15 year-old cat, and a 13-14 year-old dog.
- Aging in dogs is breed specific.
- Prevalence is similar to that seen in humans: an 85 year-old human is roughly equivalent to a 15 year-old cat, and a 13-14 year-old dog.
Pathology
- A number of changes are seen in the brains of geriatric animals which may cause the signs of CDS.
- Vascular insufficiency leads to:
- Hypoxia
- Increased free redical production
- Deposition of amyloid plaques
- Modification of other brain proteins
- Vascular insufficiency leads to:
Treatment
- There are no published studies related to treatment of CDS in animals.
- Potential therapies include:
- Dietary modification
- Diets are enriched with antioxidants, vitamin E, beta-carotene and essential fatty acids.
- Environmental stimulation
- Drugs
- Selegiline
- Propentofylline
- Nicergoline
- Dietary modification