Central Nervous System - Metabolic Pathology

Metabolic Disease

• Forebrain function may be altered by a variety of metabolic disturbances, including:
  • Liver disease
  • Renal disease
  • Pancreatic disease
  • Hypo/hyper-glycaemia
  • Electrolyte abnormalities
  • Acid-base abnormalities.
• Generally, the nervous system signs of these diseases are diffuse and often symmetrical in the rostrotentorial area.
• Strucural disease of the brain may result
  • This may cause focal neurological deficits.

Diagnosis

• Clinical signs are used in conjunction with biochemical studies of the affected organs or systems.