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== Introduction<br> ==
This is a rare syndrome is a complex of Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.<br>
[[Category:Salivary Glands - Pathology]]
Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. <br>
[[Category:To_Do_-_Clinical]]
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== Clinical Signs<br> ==
Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.<br>
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== Diagnosis<br> ==
Diagnosis by elimination of all other causes of these clinical signs.<br>
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== Treatment<br> ==
None.<br>
Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.<br>
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== Prognosis<br> ==
Guarded to Poor<br>
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== References<br> ==
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial<br>Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier. <br>Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins. <br><br>
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[[Category:Salivary_Glands_-_Pathology]] [[Category:To_Do_-_Review]]