Difference between revisions of "Budd-Chiari-Like Syndrome"
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| − | == Introduction | + | {{review}} |
| + | == Introduction == | ||
This condition is an acquired or congenital obstruction to the caudal vena cava affecting venous return to the right side of the heart. The venous obstruction causes increased pressure within the liver allowing for fluid and protein to leak out of the hepatic sinusoids into the surrounding areas. | This condition is an acquired or congenital obstruction to the caudal vena cava affecting venous return to the right side of the heart. The venous obstruction causes increased pressure within the liver allowing for fluid and protein to leak out of the hepatic sinusoids into the surrounding areas. | ||
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== Signalment == | == Signalment == | ||
| − | '''Dogs:''' Young dogs under two years old; | + | '''Dogs:''' Young dogs under two years old; male > female. There have been no reported cases in cats. |
| − | |||
| − | == Clinical Signs | + | == Clinical Signs == |
| − | Clinical signs can be vague and similar to other disease but include ascites (with modified transudate), hepatomegaly, lethargy, abdominal distension and abdominal pain and anorexia. | + | Clinical signs can be vague and similar to other disease but include ascites (with modified transudate), hepatomegaly, lethargy, abdominal distension and abdominal pain and anorexia. |
| − | |||
| − | == Diagnosis | + | == Diagnosis == |
| − | Blood tests may reveal elevated liver | + | '''Blood tests''' may reveal elevated liver enzymes and the presence of a [[Stress Leukogram|stress leukogram]]. If ascites is present, examination of this will prove it to be a [[Modified Transudate|modified transudate]]. '''Radiography''' will show the presence of ascites and an enlarged Caudal Vena Cava. If an '''electrocardiograph''' (ECG) is performed, this may demonstrate right atrial enlargement (tall P waves). '''Echocardiography''' may show an obstruction. '''Abdominal ultrasound''' will also demonstrate ascites, plus hepatomegaly and enlarged hepatic veins. Angiography can be used to visualise blood flow. |
| − | |||
== Treatment == | == Treatment == | ||
| − | Surgery is indicated for some cases,but is very risky. Medical treatment to provide supportive therapy, includes regular abdominocentesis, plus the use of drugs, furosemide (a diuretic) and enalapril, an ACE inhibitor. | + | Surgery is indicated for some cases, but is very risky. Medical treatment to provide supportive therapy, includes regular abdominocentesis, plus the use of drugs, furosemide (a diuretic) and enalapril, an ACE inhibitor. |
| − | |||
== Prognosis == | == Prognosis == | ||
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Excellent with an experienced surgeon, but poor if only medical therapy is used. | Excellent with an experienced surgeon, but poor if only medical therapy is used. | ||
| − | |||
| − | == References | + | == References == |
| − | Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) | + | Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition), W.B. Saunders Company |
| − | + | Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2), W.B. Saunders Company | |
| − | [[Category:Venous_Pathology]] [[Category: | + | Fossum, T. W. et. al. (2007) Small Animal Surgery (Third Edition), Mosby Elsevier |
| + | |||
| + | Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial | ||
| + | |||
| + | Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition), Mosby Elsevier. | ||
| + | |||
| + | |||
| + | |||
| + | [[Category:Venous_Pathology]] [[Category:Expert_Review]] [[Category:Vascular_Diseases_-_Dog]] | ||
Revision as of 16:19, 21 March 2011
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
Introduction
This condition is an acquired or congenital obstruction to the caudal vena cava affecting venous return to the right side of the heart. The venous obstruction causes increased pressure within the liver allowing for fluid and protein to leak out of the hepatic sinusoids into the surrounding areas.
Signalment
Dogs: Young dogs under two years old; male > female. There have been no reported cases in cats.
Clinical Signs
Clinical signs can be vague and similar to other disease but include ascites (with modified transudate), hepatomegaly, lethargy, abdominal distension and abdominal pain and anorexia.
Diagnosis
Blood tests may reveal elevated liver enzymes and the presence of a stress leukogram. If ascites is present, examination of this will prove it to be a modified transudate. Radiography will show the presence of ascites and an enlarged Caudal Vena Cava. If an electrocardiograph (ECG) is performed, this may demonstrate right atrial enlargement (tall P waves). Echocardiography may show an obstruction. Abdominal ultrasound will also demonstrate ascites, plus hepatomegaly and enlarged hepatic veins. Angiography can be used to visualise blood flow.
Treatment
Surgery is indicated for some cases, but is very risky. Medical treatment to provide supportive therapy, includes regular abdominocentesis, plus the use of drugs, furosemide (a diuretic) and enalapril, an ACE inhibitor.
Prognosis
Excellent with an experienced surgeon, but poor if only medical therapy is used.
References
Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition), W.B. Saunders Company
Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2), W.B. Saunders Company
Fossum, T. W. et. al. (2007) Small Animal Surgery (Third Edition), Mosby Elsevier
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial
Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition), Mosby Elsevier.