Difference between revisions of "Actinobacillosis - Pig Flashcards"

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<FlashCard questions="11">
 
<FlashCard questions="11">
|q1=What causes actinobacillosis in pigs?
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|q1=What is a prion (PrP)?
|a1= ''Actinobacillus suis'' - a beta-haemolytic Gram-negative bacterium.
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|a1=
|l1=Actinobacillus suis#Introduction
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A prion (PrP) is a protein that occurs normally in the nervous and lymphoreticular tissues.  When is changes conformation (PrP<sup>sc</sup>/PrP<sup>Res</sup>) it becomes an infectious agent and causes degeneration of neurological tissue.
|q2=Is actinobacillosis a zoonosis?
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|l1=Bovine Spongiform Encephalopathy#Introduction
|a2=It is not considered a zoonosis but there has been a report of human infection after a pig bite
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|q2=How are cattle exposed to BSE?
|l2=Actinobacillosis - Pig#Introduction
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|a2=
|q3=What herds are more susceptible to ''A.suis''?
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Through the feeding of ruminant-derived protein within feedstuffs such as meat and bone meal (MBM).
|a3=High health status herds with lower immune challenges.
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|l2=Bovine Spongiform Encephalopathy#Introduction
|l3=Actinobacillosis - Pig#Signalment
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|q3=What is the average incubation time of BSE?
|q4=What environmental factors can exacerbate this disease?
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|a3=
 +
4-5 years
 +
|l3=Bovine Spongiform Encephalopathy#Signalmet
 +
|q4=What are the main clinical signs of BSE in cattle?
 
|a4=
 
|a4=
*Temperature fluctuation
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* Progressive neurological and behavioural changes
*High humidity
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* Changes in sensation and temperament (increased agression)
*Mixing of pigs of different ages
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* Progressive weakness and hind-limb ataxia
*Overcrowding
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* Decreased milk yield
Genetic make up and immune status can also influence infectivity rate and clinical signs.
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|l4=Bovine Spongiform Encephalopathy#Clinical signs
|l4=Actinobacillosis - Pig#Signalmet
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|q5=What area of the brain do prions mainly accumulate in?
|q5=What age ranges of pigs are affected by this disease?
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|a5= In the medulla oblongata (Obex)
|a5= The disease affects suckling, weanling and fattening pigs, and adult pigs and it is thought that it colonises piglets within the first three weeks of life.
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|l5=Bovine Spongiform Encephalopathy#Diagnosis
|l5=Actinobacillosis - Pig#Introduction
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|q6=Can serological tests be used for BSE?
|q6=What clinical signs can be associated with actinobacillosis?
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|a6= No, because BSE does not cause an immune or inflammatory response.
|a6=  
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|l6=Bovine Spongiform Encephalopathy#Diagnosis
* Lethargy, depression, '''erysipelas-like lesions''', abscesses, haemorrhage, vomiting/regurgitation and '''lameness''', '''multiple joint swelling''', dysphagia, lymphadenopathy, '''anorexia''', unthriftiness, '''pneumonia''' and '''sudden death'''
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|q7=How is BSE diagnosed?
*'''Cardiorespiratory signs:''' tachycardia, murmurs, changes in heart rate, purulent or serous occulonasal discharges, sneezing, coughing, abnormal lung sounds, dyspnoea, '''cyanosis''' and open mouthed breathing
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|a7=  
*'''Aural purulent mucoid discharge''',rubbing and scratching their ears and deafness
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* Observation of clinical signs
*Neurological signs such as head tilt, circling, '''temors''', '''paraparesis''' and '''ataxia'''
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* Postmortem and the presence of bilateral symmetrical vacuolation in the grey matter
*Ocular signs such as '''corneal oedema''' and '''ulceration'''
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* Western Blot Test (detection of PrP<sup>Res</sup>)
In '''sows''' it can cause '''agalactia, mastitis, abortions, still births''' or '''weak piglets'''.
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* Elisa Test
|l6=Actinobacillosis - Pig#Clinical Signs
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|l7=Bovine Spongiform Encephalopathy#Diagnosis
|q7=How can ''actinobacillus'' be diagnosed?
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|q8=What are the most important control measures for BSE?
|a7= By the isolation of ''A. suis'', from '''culturing infected tissue'''.
 
|l7=Actinobacillosis - Pig#Diagnosis
 
|q8=What can be seen on post mortem with this disease?
 
 
|a8=  
 
|a8=  
*Serous or '''fibrinous exudates''' in the thorax and pericardium
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* The 1988 feed ban prohibiting the feeding of ruminant derived meat and bone meal (MBM) to ruminants
*'''Ecchymotic haemorrhages''' in kidneys, lungs, liver, spleen and other organisms
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* Post mortem testing schemes
|l8=Actinobacillosis - Pig#Diagnosis
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* Culling of infected cohort animals
|q9=What are the differential diagnosis for ''actinobacillosis'' in pigs?
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|l8=Bovine Spongiform Encephalopathy#Diagnosis
|a9=  
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|q9=Is BSE a zoonosis?
*Actinobacillus pleuropneumoniae
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|a9= Yes, there is evidence to suggest that humans are at risk of developing variant Creutzfeldt-Jakob Disease (vCJD)from eating BSE infected meat.
*Erysipelas
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|l9=Bovine Spongiform Encephalopathy#Control
*Glasser's Disease
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|q10= What measures have been put in place to reduce the risk of humans developing variant Creutzfeldt-Jakob Disease (vCJD)?
*Streptococcus suis
 
*Mulberry Heart Disease
 
|l9=Actinobacillosis - Pig#Diagnosis
 
|q10=How is actinobacillosis in pigs treated?
 
 
|a10=  
 
|a10=  
*'''Ceftioufur, gentamicin''' and '''trimethoprim/sulfadiazine''' (good sensitivity)
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*All visible nervous and lymphatic tissue that are classified as '''specified risk materials (SRM)''' are removed during the processing of cattle
*Ampicillin, neomycin, sulfadimethoxine and tiamulin (moderate sensitivity)
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*The removal of any suspect animals from the human food chain. 
Culture and sensitivity is recommended.
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*In 1996, cattle over the age of 30 months were eliminated from the food chain within the UK under the '''‘over thirty months scheme’''' (OTMS).  This ban has now been lifted and it is now compulsory to test all cattle over the age of 48months for BSE.
|l10=Actinobacillosis - Pig#Treatment
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|l10=Bovine Spongiform Encephalopathy#Control
|q11=How is actinobacillosis in pigs controlled?
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|q11=What are the specified risk material (SRM) for cattle?
 
|a11=  
 
|a11=  
Currently there is no commercial vaccine for ''A. suis''.  '''Routine biosecurity''' and '''disinfection''' should be followed and maintained. 
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*Brain
|l11=Actinobacillosis - Pig#Control
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*Eyes (retina)
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*Trigeminal ganglia
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*Spinal cord
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*Dorsal root ganglia
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*Mesentery
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*Intestines (duodenum to rectum)
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*Tonsils
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|l11=Bovine Spongiform Encephalopathy#Control
 
</FlashCard>
 
</FlashCard>
  
==Further links==
 
[[Actinobacillus suis| Actinobacillus suis'']]
 
  
[[Actinobacillus suis Flashcards| ''Actinobacillus suis'' Flashcards]]
 
  
 
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[[Category: Pig Flashcards]]
[[Category:Pig Flashcards]]
 
 
[[Category:CABI Flashcards]]
 
[[Category:CABI Flashcards]]
[[Category:Respiratory Diseases Flashcards]] [[Category:Integumentary Diseases Flashcards]] [[Category:Neurological Diseases Flashcards]] [[Category:Reproductive Diseases Flashcards]]
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[[Category: To Do - Jaimie Meagor]]

Revision as of 20:12, 23 June 2011

Question Answer Article
What is a prion (PrP)? Link to Article
How are cattle exposed to BSE? Link to Article
What is the average incubation time of BSE? Link to Article
What are the main clinical signs of BSE in cattle? Link to Article
What area of the brain do prions mainly accumulate in? Link to Article
Can serological tests be used for BSE? Link to Article
How is BSE diagnosed? Link to Article
What are the most important control measures for BSE? Link to Article
Is BSE a zoonosis? Link to Article
What measures have been put in place to reduce the risk of humans developing variant Creutzfeldt-Jakob Disease (vCJD)? Link to Article
What are the specified risk material (SRM) for cattle? Link to Article