Difference between revisions of "Mycoplasma hyopneumoniae"

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{{Taxobox
 
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|name = ''Mycoplasma hyopneumoniae''
 
|name = ''Mycoplasma hyopneumoniae''
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==Introduction==
 
==Introduction==
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'''''Mycoplasma hyopneumoniae''''' is a very '''small, gram positive [[Bacteria|bacterial]] pathogen.''' It is round in shape and stores its DNA in a nucleolus and in fibrillar cytoplasmic material.
 
  
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Culture of ''M. hyopneumoniae'' is difficult and time-consuming and requires specialised media. It grows slowly, requires 5-10% carbon dioxide and produces an acid colour shift. Because of the time taken, contamination is very common, especially with other [[Mycoplasmas]].
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''M.hyopneumoniae'' is a species of the ''[[Mycoplasmas species - Overview|Mycoplasmas]]'' genus. It causes [[Enzootic Pneumonia - Pigs|Enzootic pneumonia of pigs]].
  
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==Pathogenesis==
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''M.hyopneumoniae'' occurs in unfavourable conditions with poor ventilation, overcrowding and temperature fluctuations. It results in stunted growth rates, coughing and occasionally respiratory distress due to consolidation in apical and cardiac lung lobes.
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''M. hyopneumoniae'' '''adheres to the cilia of the respiratory tract'''<ref>Zielinski, G. C., Ross, R. F (1993) '''Adherence of ''Mycoplasma hyopneumoniae'' to porcine ciliated respiratory tract cells.''' ''American J Vet Research'', 54(8):1262-1269; 27</ref>, causing '''ciliostasis, clumping and loss.'''<ref>Debey, M. C., Ross, R. F (1994) '''Ciliostasis and loss of cilia induced by ''Mycoplasma hyopneumoniae'' in porcine tracheal organ cultures'''. ''Infection and Immunity'', 62(12):5312-5318; 33</ref> This is followed by '''loss of epithelial cells and goblet cells'''. <ref>Debey, M. C., Jacobson, C. D., Ross, R. F (1992) '''Histochemical and morphologic changes of porcine airway epithelial cells in response to infection with ''Mycoplasma hyopneumoniae'''''. ''American Journal of Veterinary Research'', 53(9):1705-1710; 28</ref> This '''reduces the efficacy of mucociliary clearance and allows the colonisation''' of the secondary pathogens that are usually involved in [[Enzootic Pneumonia - Pigs|Enzootic Pneumonia]].
 
  
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''M. hyopneumoniae'' also alters many other aspects of the host’s immune system, including [[B cells|B]] and [[T cells|T lymphocyte]] driven immunity, alveolar [[macrophages]] and the production of pro-inflammatory cytokines.
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Immunofluorescence of lung tissue and complement fixation test or ELISA can be used for identification of ''M.hyopneumoniae''. Treatment includes in-feed antibiotics such as tylosin, lincomycin and tiamulin. It is absent in specific-pathogen-free herds.
  
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'''Mononuclear infiltration''' of peribronchiolar and perivascular areas is the basis of pneumonic lesions and often causes the formation of lymphoid nodules when disease is chronic, as it often is.  
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
  
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Pathogenicity and severity of disease are stipulated by the presence and interaction of ''M. hyopneumoniae'' with other pathogens.
 
  
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==Diseases==
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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''M. hyopneumoniae'' causes '''[[Enzootic Pneumonia - Pigs|enzootic pneumonia in pigs]]'''.
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{{Learning
 
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|flashcards = [[Mycoplasma hyopneumoniae Flashcards|''M. hyopneumoniae'' Flashcards]]
 
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|literature search=
 
 
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Mycoplasma+hyopneumoniae%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=69&y=10&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all ''Mycoplasma hyopneumoniae'' publications]
 
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Mycoplasma+hyopneumoniae%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=69&y=10&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all ''Mycoplasma hyopneumoniae'' publications]
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==References==
 
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<references/>
 
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{{CABI source
 
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|datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=74548&loadmodule=datasheet&page=2144&site=160 ''Mycoplasma hyopneumoniae'']
 
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|date =25 June 2011
 
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{{review}}
 
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{{OpenPages}}
 
  
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[[Category:CABI Expert Review]][[Category:CABI AHPC Pages]]
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[[Category:To Do - CABI]]
 
[[Category:Mycoplasmas]]
 
[[Category:Mycoplasmas]]

Revision as of 02:08, 25 June 2011

Mycoplasma hyopneumoniae
Phylum Firmicutes
Class Mollicutes
Order Mycoplasmatales
Family Mycoplasmataceae
Genus Mycoplasma
Species M.hyopneumoniae

Introduction

M.hyopneumoniae is a species of the Mycoplasmas genus. It causes Enzootic pneumonia of pigs.

M.hyopneumoniae occurs in unfavourable conditions with poor ventilation, overcrowding and temperature fluctuations. It results in stunted growth rates, coughing and occasionally respiratory distress due to consolidation in apical and cardiac lung lobes.

Immunofluorescence of lung tissue and complement fixation test or ELISA can be used for identification of M.hyopneumoniae. Treatment includes in-feed antibiotics such as tylosin, lincomycin and tiamulin. It is absent in specific-pathogen-free herds.

Literature Search

CABI logo.jpg


Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).


Mycoplasma hyopneumoniae publications

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