'''Aetiology''' - it may be infectious, parasitic, congenital or nutritional (e.g. calcification of large vessels)
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'''Clinical signs''' - Clinical signs of cardiovascular disease are usually non-specific such as anorexia and weight loss. Signs such as swelling in the area of the heart, peripheral oedema and ascites warrant investigation of the cardiovascular system.
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'''Diagnosis'''
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*History
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*[[Lizard Physical Examination|Physical examination]], especially auscultation
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*Blood culture
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*Radiography
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*Ultrasound
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*Doppler flow detector
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*Electrocardiography though interpretation may be a problem
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*[[Lizard Necropsy|Necropsy]]
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'''Treatment''' - Includes supportive treatment, antimicrobial if infectious, and correction of [[Lizard Husbandry Requirements|husbandry]].