Difference between revisions of "Corynebacterium species"
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| − | # | + | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> |
| + | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
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| + | *''C. pyogenes'' in [[Joints - inflammatory#In Sheep|arthritis]] of sheep post-dipping joint infection and [[Joints - inflammatory#In Pigs|arthritis in pigs]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]] | ||
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| + | *''Corynebacterium pseudotuberculosis'' may cause [[Muscles - inflammatory#Abscesses|myositis]] | ||
| + | *''Corynebacterium pseudotuberculosis'' in [[Bacterial skin infections#Deep pyoderma|deep pyoderma]] | ||
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| + | ===Overview=== | ||
| + | |||
| + | *Common inhabitants of skin and mucous membranes of animals | ||
| + | *Opportunistic infections | ||
| + | *Cause pyogenic infections | ||
| + | *Most species host specific | ||
| + | |||
| + | |||
| + | ===Characteristics=== | ||
| + | |||
| + | *Small, tough, Gram positive rods | ||
| + | *Pleomorphic | ||
| + | *Cluster together to resemble Chinese characters - coryneform morphology | ||
| + | *Known as diphtheroids | ||
| + | *Catalase positive, oxidase negative | ||
| + | *Facultative anaerobes | ||
| + | *Require enriched media for growth | ||
| + | *Non-motile | ||
| + | |||
| + | |||
| + | ===Pathogenesis and pathogenicity=== | ||
| + | |||
| + | *Pyogenic causing | ||
| + | |||
| + | |||
| + | ===Clinical infections=== | ||
| + | |||
| + | *Infection follows tissue trauma | ||
| + | *Suppurative lesions | ||
| + | *''C. pseudotuberculosis'' casues caseous lymphadenitis in sheep | ||
| + | *Carried on skin of sheep | ||
| + | *Produces a phospholipase toxin | ||
| + | *Infection through shearing wounds | ||
| + | *Facultative intracellular pathogen inside macrophages | ||
| + | *Ulcerative lymphangitis in horses | ||
| + | |||
| + | |||
| + | ===Diagnosis=== | ||
| + | |||
| + | *Colony characteristics: | ||
| + | **''C. bovis'': lipophilic bacterium; small, white, dry, non-haemolytic colonies on plates inoculated with bovine milk | ||
| + | **''C. kutscheri'': white colonies; occasionally haemolytic | ||
| + | **''C. pseudotuberculosis'': small, white coloniess surrounded by narrow zone of complete haemolysis; colonies become dry and cream-coloured | ||
| + | **''C. renale'': small, non-haemolytic colonies after 24 hours; pigment produced after 48 hours | ||
| + | *Biochemical reactions: | ||
| + | **Certain strains of ''C. pseudotuberculosis'' reduce nitrates | ||
| + | **All pathogenic strains except ''C. bovis'' produce urease | ||
| + | *Enhancement of haemolysis produced by ''C. pseudotuberculosis'' when inoculated across a streak of ''Rhodococcus equi'' | ||
Revision as of 12:08, 18 May 2008
- C. pyogenes in arthritis of sheep post-dipping joint infection and arthritis in pigs and arthritis in cattle
- Corynebacterium pseudotuberculosis may cause myositis
- Corynebacterium pseudotuberculosis in deep pyoderma
Overview
- Common inhabitants of skin and mucous membranes of animals
- Opportunistic infections
- Cause pyogenic infections
- Most species host specific
Characteristics
- Small, tough, Gram positive rods
- Pleomorphic
- Cluster together to resemble Chinese characters - coryneform morphology
- Known as diphtheroids
- Catalase positive, oxidase negative
- Facultative anaerobes
- Require enriched media for growth
- Non-motile
Pathogenesis and pathogenicity
- Pyogenic causing
Clinical infections
- Infection follows tissue trauma
- Suppurative lesions
- C. pseudotuberculosis casues caseous lymphadenitis in sheep
- Carried on skin of sheep
- Produces a phospholipase toxin
- Infection through shearing wounds
- Facultative intracellular pathogen inside macrophages
- Ulcerative lymphangitis in horses
Diagnosis
- Colony characteristics:
- C. bovis: lipophilic bacterium; small, white, dry, non-haemolytic colonies on plates inoculated with bovine milk
- C. kutscheri: white colonies; occasionally haemolytic
- C. pseudotuberculosis: small, white coloniess surrounded by narrow zone of complete haemolysis; colonies become dry and cream-coloured
- C. renale: small, non-haemolytic colonies after 24 hours; pigment produced after 48 hours
- Biochemical reactions:
- Certain strains of C. pseudotuberculosis reduce nitrates
- All pathogenic strains except C. bovis produce urease
- Enhancement of haemolysis produced by C. pseudotuberculosis when inoculated across a streak of Rhodococcus equi