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==Introduction==

==Introduction==

Hyalisation of muscle fibrils of skeletal, intercostal, diaphragmatic and cardiac muscles.  Histologically there is '''[[Zenker Degeneration - Pathology|Zenker degeneration]]''' and occasionally also '''[[Myocardial Mineralisation|dystrophic calcification]]'''.

Hyalisation of muscle fibrils of skeletal, intercostal, diaphragmatic and cardiac muscles.  Histologically there is '''[[Zenker Degeneration|Zenker degeneration]]''' and occasionally also '''[[Myocardial Mineralisation|dystrophic calcification]]'''.

Grossly the condition is seen as grey/yellow streaks on the innermost part of the myocardium.   

Grossly the condition is seen as grey/yellow streaks on the innermost part of the myocardium.   

The condition is associated with '''Vitamin/Selenium deficiency'''.  Also known as [[Muscles Degenerative - Pathology#Nutritional myopathy|'''nutritional myopathy''']] or '''[[White Muscle Disease - Pathology|White muscle disease]]'''.   

The condition is associated with '''Vitamin/Selenium deficiency'''.  Also known as [[:Category:Muscles - Degenerative Pathology|'''nutritional myopathy''']] or '''[[White Muscle Disease|White muscle disease]]'''.   

The myocardium of the left ventricle is most affected as it has the largest metabolic demand and so the largest production of anti-oxidants and the greatest need for Vitamin E/Selenium.  This manifests clinically as left sided heart failure with clinical signs:

The myocardium of the left ventricle is most affected as it has the largest metabolic demand and so the largest production of anti-oxidants and the greatest need for Vitamin E/Selenium.  This manifests clinically as left sided heart failure with clinical signs:

*Pulmonary oedema.

*Pulmonary oedema.

==Test yourself with the Mycocardial Pathology Flashcards==

 

|flashcards = [[Myocardial Pathology Flashcards]]

[[Myocardial_Pathology_Flashcards_-_Pathology|Myocardial Pathology Flashcards]]

 

[[Category:Cardiovascular_System_-_Metabolic_Pathology]][[Category:Myocardial_Pathology]]

[[Category:Cardiovascular_System_-_Metabolic_Pathology]][[Category:Myocardial_Pathology]]