Difference between revisions of "Joint Response to Injury"

Revision as of 19:40, 18 August 2008

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-===Causes of injury ===
+{{toplink
+|backcolour =CDE472
-*Trauma
+|linkpage =Musculoskeletal System - Pathology
-*Instability
+|linktext =Musculoskeletal System
-*Lubrication failure
+|maplink = Musculoskeletal System (Content Map) - Pathology
-*Infectious organisms
+|pagetype =Pathology
-*Immune-mediated disease
+|sublink1=Joints - Pathology
+|subtext1=JOINTS
-===Reaction to injury===
+}}
+<br>
-*[[Joints - Anatomy & Physiology#Articular cartilage|Articular cartilage]] has limited ability to regenerate
-**Superficial defects are long standing
-***Chondrocyte hyperplasia is ineffective at filling the defect
-***Non-painful
-**Defects reaching subchondral bone
-***Filled with vascular fibroous tissue undergoing [[Cell Growth Disorders#Metaplasia|metaplasia]] into cartilage
-***Painful
-**Fibrillation - loss of proteoglycans -> condensation of collagen fibres -> fraying of surface
-**Eburnation - loss of articular cartilage -> exposure of subchondral bone -> becomes dense and polished
-*Synovial membranes respond by:
-**Villous hypertrophy
-***+/- synovitis
-**Hyperplasia
-[[Category:Joints - Pathology|A]]