Difference between revisions of "Innate Immunity Flashcards"

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===Actions and Tools of the Innate Immune System===
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{{toplink
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<FlashCard questions="14">
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|backcolour = f5fffa
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|q1=True or False: The innate immune system responds quicker to infection than the adaptive immune system
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|linkpage =Innate Immune System - WikiBlood
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|a1=True
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|linktext =INNATE IMMUNE SYSTEM
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|l1=Innate Immune System - Introduction
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|sublink1 =Flash Cards - WikiBlood
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|q2=Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?
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|subtext1 =WIKIBLOOD FLASHCARDS
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|a2=
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|pagetype =Blood
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*Lipopolysaccharides or Gram Negative bacteria
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}}
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*Peptidoglycans of gram-positive bacteria
 
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*Mannose sugars
 
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*D-isoform amino acids
 
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|l2=Recognition of Microorganisms
 
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|q3=What recognises PAMPs?
 
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|a3=Pattern recognition receptors (PRRs)
 
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|l3=Recognition of Microorganisms
 
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|q4=Where in the cell are Toll-Like Receptors (TLRs) located?
 
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|a4=Cell membrane
 
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|l4=Recognition of Microorganisms
 
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|q5=Where in the cell are NOD2 receptors located?
 
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|a5=Cell cytoplasm
 
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|l5=Recognition of Microorganisms
 
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|q6=Which catabolic enzymes digest microbes after phagocytosis?
 
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|a6=
 
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*Glycosidases
 
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*Lipases
 
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*Proteases
 
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|l6=Phagocytosis
 
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|q7=True or False: Lysosomes do not use energy when they kill microbes
 
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|a7=
 
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*False
 
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*Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way
 
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|l7=Phagocytosis
 
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|q8=Name two physical barriers of the innate immune system
 
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|a8=
 
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*Skin
 
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*Mucous membranes
 
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|l8=Innate Immunity Barriers
 
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|q9=Name 3 biochemical barriers of the innate immune system
 
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|a9=
 
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*Lactic and fatty acids
 
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*Enzymes
 
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*Mucous
 
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|l9=Innate Immunity Barriers
 
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|q10=What is the function of commensal organisms?
 
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|a10=
 
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*Produce natural antibiotics
 
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*Outcompete pathogens at epithelial and mucosal surfaces
 
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|l10=Innate Immunity Barriers
 
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|q11=Complete the sentence about commensal organisms:
 
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<p>When commensals are disturbed, infection with ??? organisms is ???</p>
 
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|a11=
 
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*opportunistic
 
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*increased
 
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|l11=Innate Immunity Barriers
 
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|q12=Name the three main humoral factors and their principal action
 
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|a12=
 
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*Lysozyme
 
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**Digests bacterial cell walls
 
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*Complement
 
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**Promotes phagocytosis or lysis of invading organisms
 
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*Interferons
 
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**Make uninfected cells resistant to infection and enhances expression of MHC molecules
 
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|l12=Humoral Factors of Innate Immune System
 
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|q13=Which granulocytes are components of the innate immune response to infection?
 
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|a13=
 
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*Neutrophils
 
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*Eosinophils
 
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*Basophils/mast cells
 
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|l13=Innate Immunity Cellular Responses
 
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|q14=Which other cells are components of the innate immune response to infection?
 
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|a14=Monocytes
 
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*Tissue mast cells
 
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*Macrophages
 
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|l14=Innate Immunity Cellular Responses
 
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</FlashCard>
 
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===Innate Immunity to Viruses===
 
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<FlashCard questions="4">
 
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|q1=What is the main element of a viral attack which the innate immune system can recognise?
 
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|a1=Double stranded RNA (dsRNA)
 
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|l1=Innate Immunity to Viruses
 
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|q2=Where are TLR3's located in the cell and what do they recognise?
 
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|a2=
 
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*Cell surface
 
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*Double stranded RNA (dsRNA)
 
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|l2=Innate Immunity to Viruses
 
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|q3=What are the funtions of Type I Interferon production in response to a viral attack?
 
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|a3=
 
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*Increases mRNA degredation
 
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*Inhibits protein synthesis
 
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*Increases antigen presentation to antibody
 
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|l3=Innate Immunity to Viruses
 
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|q4=Which cells are produced as the final line of response to viral attack and which cells do they target?
 
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|a4=
 
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*Natural Killer cells (NK cells)
 
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*Targets cells with decreased levels of MHC on their surface
 
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|l4=Innate Immunity to Viruses
 
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</FlashCard>
 
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===Innate Immunity to Bacteria===
 
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<FlashCard questions="2">
 
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|q1=What effects does the release of inflammatory cytokines have on the infected area?
 
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|a1=
 
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*White blood cell influx
 
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*Vasodilation
 
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*Increase in vascular permeability
 
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*Sustains a rise in core temperature
 
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*Mediates the release of acute phase proteins from the liver
 
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*Mediates bone marrow mobilisation
 
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|l1=Innate Immunity to Bacteria
 
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|q2=Which cell is the most important effector cell in the innate response to bacterial infection?
 
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|a2=Neutrophils
 
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|l2=Innate Immunity to Bacteria
 
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</FlashCard>
 
  
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<br><br>
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==<font color="purple">Actions and Tools of the Innate Immune System</font>==
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{{Jim Bee 2007}}
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{| border="3" cellpadding="8"
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[[Category:Immunology Flashcards]]
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!width="400"|'''Question'''
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[[Category:Innate Immune System|Z]]
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!width="400"|'''Answer'''
 +
!width="150"|'''Article'''
 +
|-
 +
|<big>'''True or False: The innate immune system responds quicker to infection than the adaptive immune system'''
 +
||<font color="white"> <big>
 +
*'''''True'''''
 +
||[[Innate Immune System - WikiBlood#Introduction|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?'''
 +
||<font color="white"> <big>
 +
*'''''Lipopolysaccharides or Gram Negative bacteria'''''
 +
*'''''Peptidoglycans of gram-positive bacteria'''''
 +
*'''''Mannose sugars'''''
 +
*'''''D-isoform amino acids'''''
 +
||[[Innate Immune System - WikiBlood#Recognition of Microorganisms|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''What recognises PAMPs?'''
 +
||<font color="white"> <big>
 +
*'''''Pattern recognition receptors (PRRs)'''''
 +
||[[Innate Immune System - WikiBlood#Recognition of Microorganisms|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''Where in the cell are Toll-Like Receptors (TLRs) located?'''
 +
||<font color="white"> <big>
 +
*'''''Cell membrane'''''
 +
||[[Innate Immune System - WikiBlood#Recognition of Microorganisms|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''Where in the cell are NOD2 receptors located?'''
 +
||<font color="white"> <big>
 +
*'''''Cell cytoplasm'''''
 +
||[[Innate Immune System - WikiBlood#Recognition of Microorganisms|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''Which catabolic enzymes digest microbes after phagocytosis?'''
 +
||<font color="white"> <big>
 +
*'''''Glycosidases'''''
 +
*'''''Lipases'''''
 +
*'''''Proteases'''''
 +
||[[Innate Immune System - WikiBlood#Phagocytosis|<span title="Answer article">Link to Answer Article</span>]]
 +
|-
 +
|<big>'''True or False: Lysosomes do not need energy when they kill microbes'''
 +
||<font color="white"> <big>
 +
*'''''False'''''
 +
*'''''Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way'''''
 +
||[[Innate Immune System - WikiBlood#Phagocytosis|<span title="Answer article">Link to Answer Article</span>]]
 +
|}

Revision as of 11:44, 4 September 2008

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INNATE IMMUNE SYSTEM
WIKIBLOOD FLASHCARDS


Actions and Tools of the Innate Immune System

Question Answer Article
True or False: The innate immune system responds quicker to infection than the adaptive immune system
  • True
 Link to Answer Article
Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?
  • Lipopolysaccharides or Gram Negative bacteria
  • Peptidoglycans of gram-positive bacteria
  • Mannose sugars
  • D-isoform amino acids
 Link to Answer Article
What recognises PAMPs?
  • Pattern recognition receptors (PRRs)
 Link to Answer Article
Where in the cell are Toll-Like Receptors (TLRs) located?
  • Cell membrane
 Link to Answer Article
Where in the cell are NOD2 receptors located?
  • Cell cytoplasm
 Link to Answer Article
Which catabolic enzymes digest microbes after phagocytosis?
  • Glycosidases
  • Lipases
  • Proteases
 Link to Answer Article
True or False: Lysosomes do not need energy when they kill microbes
  • False
  • Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way
 Link to Answer Article
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