Difference between revisions of "Babesia"

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== Epidemiology ==
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*Infects a wide range of host species in different areas of the world
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Babesiosis has severe effects on cattle production in parts of the world. First of all, it prevents European breeds from being successful in tropical regions where [[Ticks|ticks]] are endemic as well as occurring sporadically in the UK and Ireland causing losses of around £8 million per year.
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* May cause haemolysis and [[General Pathology - Pigmentation and Calcification#Haemoglobin|haemoglobin pigmentation]].
 
 
=== '''Life Cycle''' ===
 
Both [[Ticks#Disease Transmission|trans-stadial]] and [[Ticks#Disease Transmission|trans-ovarian]] transmission occurs with each female [[Ticks|tick]] producing 3000 eggs and the [[Ticks|tick]] being the definitive host.
 
 
 
''Babesia'' multiplies in the red blood cells by '''budding''' and it forms 2-4 daughter cells (species dependent).
 
Giemsa blood smears can differentiate between species using 'Difquik' stain.
 
 
 
*''Babesia'' species are either small or large depending on the size of the daughter cells
 
 
 
*Small ''Babesia''
 
**E.g. ''B. divergens''
 
**E.g. ''B. gibsoni''
 
**Peripheral nucleus
 
**Obtuse angle
 
 
 
*Large ''Babesia''
 
**E.g. ''B. major''
 
**E.g. ''B. canis-complex''
 
**Central nucleus
 
**Acute angle
 
 
 
*Daughter cells disrupt the red blood cell and are released
 
**Spread and infect other red blood cells
 
 
 
*Antigen is released which adsorbs onto other red blood cells
 
**Causes haemolysis and [[Pigmentation - Pathology#Haemoglobin|haemoglobin pigmentation]]
 
**Causes haemolytic anaemia, haemoglobinuria and fever
 
 
 
===Enzootic Instability===
 
*Low rate of transmission
 
 
 
*Few infected [[Ticks|ticks]]
 
 
 
*Infrequent exposure
 
 
 
*Immunity wanes or is completely absent in many individuals
 
 
 
*Low levels of herd immunity
 
 
 
*'''Higher''' incidence of disease
 
 
 
===Enzootic Stability===
 
*High rate of transmission
 
 
 
*Many infected ticks
 
 
 
*Frequent exposure boosts immunity
 
 
 
*High level of herd immunity
 
 
 
*'''Lower''' incidence of disease
 
 
 
 
 
 
 
<big>'''[[Babesiosis - Cattle|Cattle Babesiosis]]
 
 
 
'''[[Babesia canis]]'''
 
 
 
'''[[Babesiosis - Horse|Horse Babesiosis]]'''
 
 
 
'''[[Babesiosis - Small Ruminants|Sheep and Goat Babesiosis]]
 
</big>
 
 
 
*''Babesia bovis'' myositis
 
**In cattle
 
**Infrequent muscle [[Muscle Necrosis|necrosis]]
 
 
 
==Test yourself with the Piroplasmida Flashcards==
 
 
 
[[Piroplasmida_Flashcards|Piroplasmida Flashcards]]
 
 
 
[[Category:Piroplasmida]]
 
 
 
[[Category:To_Do_-_Parasites]]
 

Revision as of 16:25, 22 September 2008

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