Difference between revisions of "Skin Other - Pathology"

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#REDIRECT[[:Category:Integumentary System - Pathology]]
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|linkpage =Integumentary System - Pathology
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|linktext =Integumentary System
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|maplink = Integumentary System (Content Map) - Pathology
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|pagetype =Pathology
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==Epidermal growth or differentiation disorders==
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===Seborrheic disease complex===
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*Abnormal cornification or function of sebaceous glands
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*Large amounts of free fatty acids and cholesterol
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*Decreased amounts of diester waxes in surface lipids
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*Bacterial population changes to pathogenic [[Staphylococcus spp.|coagulase positive staphylococci]]
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*Chronic disease affecting mainly dogs, sometimes cats and horses
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*Dry form - white to grey scales
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*Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair
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===Primary idiopathic seborrhea===
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*Abnormal cornification
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*Epidermal turnover reduced to about 2/3 of normal
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*Microscopically:  
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**Hyperkeratosis distending follicular ostia causing papillary appearance
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**Parakeratosis at edges of follicular ostia
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**Congested, oedematous dermal papillae
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**Spongiotic epidermis with leukocytes
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===Secondary seborrhea===
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*Develops secondarily to many types of disease (''e.g.'' [[Parasitic skin infections - Pathology|ectoparasites]], [[Mycotic skin infections - Pathology|fungal infections]], [[Endocrine effects on the skin - Pathology|endocrine disease]], internal disease or allergy)
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*Microscopically:
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**Hyperkeratosis and/or parakeratosis of follicles and epidermis
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**Lesions relevant to the other disease
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===Sebaceous adenitis===
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==Pigmentation disorders==
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===Hypopigmentation===
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===Hyperpigmentation===
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==Eosinophilic infiltration==
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===Eosinophilic plaques===
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===Eosinophilic granulomas===
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===Eosinophilic folliculitis and furunculosis===
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==Sterile granulomatous disorders==
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===Juvenile pyoderma===
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===Equine generalised granulomatous disease===

Revision as of 12:15, 30 October 2008



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()Map INTEGUMENTARY SYSTEM (Map)



Epidermal growth or differentiation disorders

Seborrheic disease complex

  • Abnormal cornification or function of sebaceous glands
  • Large amounts of free fatty acids and cholesterol
  • Decreased amounts of diester waxes in surface lipids
  • Bacterial population changes to pathogenic coagulase positive staphylococci
  • Chronic disease affecting mainly dogs, sometimes cats and horses
  • Dry form - white to grey scales
  • Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair

Primary idiopathic seborrhea

  • Abnormal cornification
  • Epidermal turnover reduced to about 2/3 of normal
  • Microscopically:
    • Hyperkeratosis distending follicular ostia causing papillary appearance
    • Parakeratosis at edges of follicular ostia
    • Congested, oedematous dermal papillae
    • Spongiotic epidermis with leukocytes

Secondary seborrhea

  • Develops secondarily to many types of disease (e.g. ectoparasites, fungal infections, endocrine disease, internal disease or allergy)
  • Microscopically:
    • Hyperkeratosis and/or parakeratosis of follicles and epidermis
    • Lesions relevant to the other disease

Sebaceous adenitis

Pigmentation disorders

Hypopigmentation

Hyperpigmentation

Eosinophilic infiltration

Eosinophilic plaques

Eosinophilic granulomas

Eosinophilic folliculitis and furunculosis

Sterile granulomatous disorders

Juvenile pyoderma

Equine generalised granulomatous disease