Difference between revisions of "Gastroprotective Drugs"

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==Antacids==
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These are administered orally and need frequent aministration when given to small animals. They work be chemically neutralising the acidic environment of the stomach.
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Examples are: '''magnesium carbonate, magnesium hydroxide, magnesium trisilicate, magnesium oxide, aluminium hydroxide''' and '''sodium bicarbonate'''.
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==Histamine (H<sub>2</sub>) Receptor Antagonists==
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Examples are '''cimetidine, ranitidine''' and '''famotidine'''.
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They can be administered orally or by injection and work by inhibiting the action of histamine on parietal cells. This results in reduced production of H<sup>+</sup> ions and pepsin secretion.

Revision as of 13:40, 4 November 2008



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WIKIDRUGS
BODY SYSTEMS AFFECTED BY DRUGS


Antacids

These are administered orally and need frequent aministration when given to small animals. They work be chemically neutralising the acidic environment of the stomach. Examples are: magnesium carbonate, magnesium hydroxide, magnesium trisilicate, magnesium oxide, aluminium hydroxide and sodium bicarbonate.


Histamine (H2) Receptor Antagonists

Examples are cimetidine, ranitidine and famotidine. They can be administered orally or by injection and work by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion.