Difference between revisions of "Gastritis, Acute"

From WikiVet English
Jump to navigation Jump to search
(34 intermediate revisions by 5 users not shown)
Line 1: Line 1:
{{OpenPagesTop}}
+
{{unfinished}}
==Introduction==
 
[[Image:Gastric ulceration.jpg|thumb|right|275px|Gastric ulceration - Copyright David Walker RVC]]
 
Acute inflammation of the stomach is not uncommon, especially in the dog. The cause is usually the ingestion of substances including
 
[[Gastric Foreign Objects|foreign bodies]], spoiled or contaminated food, toxic plants ,chemicals and drugs (especially [[NSAIDs|non-steroidal anti-inflammatory drugs]]).
 
Infectious, viral and bacterial causes are thought to exist in cats and dogs but have not yet been identified.
 
  
Ingestion of these substances causes disruption of the gastric mucosal barrier. This results in increased permeability, with hydrogen ions and pepsin penetrating the mucosa. An inflammatory response subsequently occurs that may damage blood vessels, resulting in the extravasation of blood and plasma into the gastric lumen. Mucosal erosions can develop due to [[Necrosis - Pathology|necrosis]] of the mucosal epithelial cells.
+
{{dog}}
 +
{{cat}}
  
Gastritis can cause contraction of gastric smooth muscle which causes spasms and pain. [[Vomiting|Vomiting]] is also a symptom following stimulation of nerve endings that connect with the vomiting centre.
+
==Signalment==
 +
*Dogs are more commonly affected than cats due to their less selective eating habits.
 +
 
 +
==Description==
 +
 
 +
Acute inflammation of the stomach is not uncommon, especially that of the canine. The cause is usually the ingestion of substances such as:
 +
*foreign objects
 +
*spoiled or contaminated food
 +
*toxic plants
 +
*chemicals
 +
*drugs (especially non-steroidal anti-inflammatory drugs)
 +
Infectious, viral and bacterial causes are thought to exist in cats and dogs but have not been identified at this point.
  
==Signalment==
+
Ingestion of these substances causes the disruption of the gastric mucosal barrier. This results in increased permeability, with hydrogen ions and pepsin penetrating the mucosa. An inflammatory response subsequently occurs that may damage blood vessels, resulting in the extravasation of blood and plasma into the gastric lumen. Mucosal erosions can develop due to necrosis of the mucosal epithelial cells.
Dogs are more commonly affected than cats due to their less selective eating habits.
+
 
 +
Gastritis can cause contraction of gastric smooth muscle which causes spasms and pain. Vomiting may result from the stimulation of nerve endings that connect with the vomiting centre.
  
 
==Diagnosis==  
 
==Diagnosis==  
 
Acute gastritis is a diagnosis of exclusion based on physical examination findings, history of ingestion of causative substances and diagnostic tests.
 
Acute gastritis is a diagnosis of exclusion based on physical examination findings, history of ingestion of causative substances and diagnostic tests.
 
 
===Clinical Signs===
 
===Clinical Signs===
Include acute vomiting (food, bile together with small amounts of blood may be present in the vomitus), anorexia, polydipsia, lethargy, depression and if severely affected dehydration.
+
*acute vomiting (food, bile together with small amounts of blood may be present in the vomitus)
 +
*anorexia
 +
*polydipsia
 +
*lethargy
 +
*depression
 +
*dehydration if severely affected
  
 
===Abdominal Palpation===
 
===Abdominal Palpation===
Line 23: Line 35:
  
 
===Laboratory Tests===
 
===Laboratory Tests===
Clinical pathology such as haematology and biochemistry can be used to rule out conditions such as [[Uraemia|uraemia]],[[Diabetes Mellitus#Diabetic Ketoacidosis| diabetic ketoacidosis]], hypoadrenocorticism], hepatic disease, hypercalcaemia and [[Pancreatitis|pancreatitis]].
+
Clinical pathology such as haematology and biochemistry can be used to rule out conditions such as uraemia, diabetic ketoacidosis, hypoadrenocorticism, hepatic disease, hypercalcaemia and pancreatitis.
  
 
===Radiography===
 
===Radiography===
Line 32: Line 44:
  
 
==Treatment==
 
==Treatment==
Many different techniques of treating acute gastritis have been described. In general, therapy is designed to rest the stomach by witholding food and maintaining the animal's fluid , electrolyte and acid/base balance.
+
Many different techniques of treating acute gastritis have been described in the literature. In general, therapy is designed to rest the stomach by witholding food and maintaining the animal's fluid , electrolyte and acid/base balance.
 
+
*Parenteral fluid therapy
Witholding food and water for 24 hours is usually sufficient to control vomiting in combination with parenteral fluid therapy to avoid dehydration.
+
*Witholding food and water for 24hours is usually sufficient to control vomiting
Small amounts of a bland diet such as boiled chicken and potato can be offered once the animal has not vomited for at least 12 hours.
+
*Small amounts of a bland diet such as boiled chicken and potato can be offered once the animal has not vomited for at least 12 hours
Gut protectants should be considered if the animal presents with haematemesis. Some examples of [[Gastroprotective Drugs|gastroprotective drugs]] include sucralfate which forms a protective barrier over the mucosal surface and also stimulates bicarbonate and mucus secretion and omeprazole which is a proton pump inhibitor that reduces gastric acid secretion.
+
*Gut protectants should be considered if the animal presents with haematemesis. Some examples include:
 +
**Sucralfate - Forms a protective barrier over the mucosal surface and also stimulates bicarbonate and mucus secretion.
 +
**Omeprazole - A proton pump inhibitor that reduces gastric acid secretion.
  
[[Emetics and Anti-Emetic Drugs#Anti-Emetics|Anti-emetics]] can be used but only if vomiting is causing pain or if unsustainable fluid and electrolyte losses occur.
 
  
 
==Prognosis==
 
==Prognosis==
The prognosis is excellent if fluid and electrolyte balance is maintained.
 
 
{{Learning
 
|Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis02679.asp, Acute gastritis]
 
|literature search = [http://www.cabdirect.org/search.html?q=title%3A%28%22gastritis%22%29+AND+title%3A%28acute%29&fq=sc%3A%22ve%22 Acute gastritis publications]
 
}}
 
  
 
==References==
 
==References==
 
Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA''
 
 
Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
 
 
 
{{review}}
 
 
{{OpenPages}}
 
 
[[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]]
 
[[Category:Expert_Review - Small Animal]][[Category:Gastric Diseases - Dog]][[Category:Gastric Diseases - Cat]]
 

Revision as of 11:03, 20 August 2009



Category:WikiClinical CanineCow
Category:WikiClinical FelineCow

Signalment

  • Dogs are more commonly affected than cats due to their less selective eating habits.

Description

Acute inflammation of the stomach is not uncommon, especially that of the canine. The cause is usually the ingestion of substances such as:

  • foreign objects
  • spoiled or contaminated food
  • toxic plants
  • chemicals
  • drugs (especially non-steroidal anti-inflammatory drugs)

Infectious, viral and bacterial causes are thought to exist in cats and dogs but have not been identified at this point.

Ingestion of these substances causes the disruption of the gastric mucosal barrier. This results in increased permeability, with hydrogen ions and pepsin penetrating the mucosa. An inflammatory response subsequently occurs that may damage blood vessels, resulting in the extravasation of blood and plasma into the gastric lumen. Mucosal erosions can develop due to necrosis of the mucosal epithelial cells.

Gastritis can cause contraction of gastric smooth muscle which causes spasms and pain. Vomiting may result from the stimulation of nerve endings that connect with the vomiting centre.

Diagnosis

Acute gastritis is a diagnosis of exclusion based on physical examination findings, history of ingestion of causative substances and diagnostic tests.

Clinical Signs

  • acute vomiting (food, bile together with small amounts of blood may be present in the vomitus)
  • anorexia
  • polydipsia
  • lethargy
  • depression
  • dehydration if severely affected

Abdominal Palpation

Severely affected animals may show signs of discomfort on palpation of the cranial abdomen.

Laboratory Tests

Clinical pathology such as haematology and biochemistry can be used to rule out conditions such as uraemia, diabetic ketoacidosis, hypoadrenocorticism, hepatic disease, hypercalcaemia and pancreatitis.

Radiography

Abdominal radiographs may be taken if the animal is severely ill and to rule out other causes such as an alimentary foreign body or obstruction.

Endoscopy

Gastroscopy may be used to visualise gastric erosions/ulcers and hyperaemia.

Treatment

Many different techniques of treating acute gastritis have been described in the literature. In general, therapy is designed to rest the stomach by witholding food and maintaining the animal's fluid , electrolyte and acid/base balance.

  • Parenteral fluid therapy
  • Witholding food and water for 24hours is usually sufficient to control vomiting
  • Small amounts of a bland diet such as boiled chicken and potato can be offered once the animal has not vomited for at least 12 hours
  • Gut protectants should be considered if the animal presents with haematemesis. Some examples include:
    • Sucralfate - Forms a protective barrier over the mucosal surface and also stimulates bicarbonate and mucus secretion.
    • Omeprazole - A proton pump inhibitor that reduces gastric acid secretion.


Prognosis

References